Post-doc fellow

Beth Israel Lahey Health • Boston, MA

13d

About The Position

When you join the growing BILH team, you're not just taking a job, you’re making a difference in people’s lives. Position Summary The Division of Nephrology/Department of Medicine seeking an experienced post-doctoral fellow/Research Associate/Sr. Research Associate, biology to advance the cutting-edge projects that are key to our goals. This individual will become a key member of Dr. Zsengeller’s team to work collaboratively on our preeclampsia/OB/GYN platform projects and to develop and optimize in-vitro/in-vivo experiments to test various drug candidates. This position provides an excellent opportunity to work at the leading edge of preeclampsia pharmacology and immunology. Candidates with extensive in-vitro and in-vivo research background in biology with a keen interest in learning new techniques and/or expanding their experience in preeclampsia are encouraged to apply. The candidate should be scientifically motivated, capable of conducting experiments independently and collaboratively. Responsibilities You will collaborate cross-functionally to evaluate various small-molecule drug candidates using in vivo preeclampsia models. Designing and performing blood pressure measurement in mice by CODA tail-cuff system Able to work with pregnant mice and assess pregnancy outcomes Performing ELISA to measure antibody responses and inflammatory markers Performing tissue staining and microscopy, as well as electron microscopy and functional EM to analyze mitochondrial dysfunction in preeclampsia Determining the effects of various immunomodulatory therapeutic molecules on transgene expression and durability Reading literature and proposing new ideas and solutions Interacting with cross-functional teams and presenting data in small and large group settings Job Description: Primary Responsibilities: - Abides by the institutional policies of BIDMC relating to health and safety, equality of opportunity and data storage and management. (essential) - As a member of the research team, actively pursues research under the supervision of a principal investigator while developing skills for independent work. (essential) - Receives training in and performs duties contributing to the investigational work of the team including formulation of research questions and design, conduct of experiments, and evaluation of results. (essential) - Prepares and publishes scientific manuscripts under direction of PI. (essential) - Develops expertise in desired lab skills/informatics/ physics/clinical research. Develops proficiency with research tools and equipment. Develops ability to work with more independence as the fellowship progresses (essential) - Develops new ideas that promote current research; brings new expertise to the research program. (essential) - teaching skills and provide supervision of students and their projects when appropriate. (essential) - Engages in collaborative meetings with other research groups. Attends and leads scientific seminars. (essential) - Learns to identify, acknowledge and correct deficiencies in one's own performance. (essential) - Under the direction of PI, pursues/secures independent funding near the end of the fellowship. (essential)

Requirements

• Doctoral Degree or M.D.
• 0-1 year of postdoctoral research experience in academic or industrial lab setting, and/or teaching assistantship in a university setting, and/or residency, and/or clinical duties beyond that of the qualifying doctoral degree.

Responsibilities

• Collaborate cross-functionally to evaluate various small-molecule drug candidates using in vivo preeclampsia models.
• Designing and performing blood pressure measurement in mice by CODA tail-cuff system
• Able to work with pregnant mice and assess pregnancy outcomes
• Performing ELISA to measure antibody responses and inflammatory markers
• Performing tissue staining and microscopy, as well as electron microscopy and functional EM to analyze mitochondrial dysfunction in preeclampsia
• Determining the effects of various immunomodulatory therapeutic molecules on transgene expression and durability
• Reading literature and proposing new ideas and solutions
• Interacting with cross-functional teams and presenting data in small and large group settings
• Abides by the institutional policies of BIDMC relating to health and safety, equality of opportunity and data storage and management.
• As a member of the research team, actively pursues research under the supervision of a principal investigator while developing skills for independent work.
• Receives training in and performs duties contributing to the investigational work of the team including formulation of research questions and design, conduct of experiments, and evaluation of results.
• Prepares and publishes scientific manuscripts under direction of PI.
• Develops expertise in desired lab skills/informatics/ physics/clinical research. Develops proficiency with research tools and equipment. Develops ability to work with more independence as the fellowship progresses
• Develops new ideas that promote current research; brings new expertise to the research program.
• teaching skills and provide supervision of students and their projects when appropriate.
• Engages in collaborative meetings with other research groups. Attends and leads scientific seminars.
• Learns to identify, acknowledge and correct deficiencies in one's own performance.
• Under the direction of PI, pursues/secures independent funding near the end of the fellowship.

What This Job Offers

• Job Type: Full-time
• Career Level: Entry Level
• Education Level: Ph.D. or professional degree
• Number of Employees: 5,001-10,000 employees