Post-Doc Fellow Lab for Regenerative Cell Therapy

Mass General BrighamBoston, MA
6dOnsite

About The Position

The George A. “Doc” Lopez, MD, Laboratory for Regenerative Cell Therapy (Lopez Lab) in the Department of Neurosurgery at Massachusetts General Hospital (MGH), a teaching affiliate of Harvard Medical School in Boston, Massachusetts, USA seeks motivated candidates to join our team at the postdoctoral research level. In 2018, the Department of Neurosurgery, MGH and the Laboratory of Molecular Neurobiology at McLean Hospital, both affiliated with Harvard Medical School, jointly completed the world's first FDA-approved autologous hiPSC-differentiated dopamine precursor cell implantation for the treatment of Parkinson's disease (N Engl J Med. 2020; 382:20 1926-1932). In 2023, the George A. “Doc” Lopez Laboratory for Regenerative Cell Therapy was established in the Department of Neurosurgery at MGH in honor of this achievement, to support ongoing and future clinical trials of cell therapy for Parkinson's disease (NCT06687837), and to develop and implement next generation cell production methods and novel cell therapies. The laboratory also focuses on disease mechanisms as a basis for developing new therapies, with an emphasis on transformative translational applications to Parkinson's disease and related neurodegenerative diseases. The laboratory includes both a GMP facility to produce clinical-grade cells for human clinical trials, and a neurobiology laboratory for preclinical research. The Laboratory is jointly directed by Scientific Director Bin Song, MD, PhD and Clinical Director Jeffrey Schweitzer, MD, PhD, both Assistant Professors of Neurosurgery of Harvard Medical School, in the Departments of Neurosurgery at Mass General Brigham.

Requirements

  • Candidate qualifications should include a PhD or MD degree in a relevant field such as neuroscience, stem cell biology, gene editing, immunology, cellular neurophysiology etc., with evidence of scholarly achievement including relevant publications.
  • Familiarity with clinical neuroscience or other biological or medical backgrounds is preferred.
  • Teamwork spirit and communication skills

Nice To Haves

  • Experience in stem cell culture and neuron differentiation
  • Experience in neurodegenerative disease animal models, neural circuit analysis, optogenetics, chemical genetics, or electrophysiology
  • Experience in gene editing, molecular biology
  • Experience in immunology
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