Portfolio Analytics Principal

Genentech•Daly City, CA

About The Position

The Portfolio Analytics Principal is a strategic finance leader who shapes how Genentech anticipates market evolution, forecasts portfolio performance, and translates complex business signals into clear, actionable insights that drive decision-making at the highest levels. This role sits at the intersection of strategy, forecasting, business performance, and advanced analytics. The candidate will partner closely with Genentech CFO, CMG finance team, GPS, Group Finance (eCOE), Investor Relations, Digital/Data & Analytics (DDA), and cross-functional teams to build a best-in-class portfolio intelligence capability—enabling Genentech to make faster, smarter, more patient-centered decisions. This role requires a combination of executive presence, analytical depth, storytelling ability, and a modern digital mindset, including automation and AI-enabled analytics.

Requirements

Bachelor’s degree in business, finance, economics, engineering, mathematics, statistics, operations research, health sciences, or related field.
10+ years experience in forecasting, insights, strategy, and/or business planning.
7+ years experience in pharma, biotech, or related industries.
Demonstrated experience leading organizational change and driving adoption of new tools/processes.
Strong executive communication skills with proven ability to influence senior stakeholders.
Deep expertise in analytics, forecasting, and business storytelling.
Ability to define and execute long-term capability roadmaps (strategy, goals, KPIs, delivery model).
Strong negotiation and interpersonal skills, with demonstrated ability to align diverse stakeholders.

Responsibilities

Serve as a trusted thought partner to senior stakeholders (Genentech CFO, CMG finance team, GPS, Group Finance (eCOE), Investor Relations, DDA, etc.), ensuring US insights align with the One Pharma Strategy, CMG priorities, and long-term enterprise commitments.
Translate business questions into analytical priorities, and ensure insights are decision-relevant, outcome-driven, and timely.
Contribute to building and scaling forward looking scenario planning: detecting early signals across market dynamics, competitive landscape, access environment, demand trends, and internal execution performance.
Integrate multiple data sources (sales, demand, payer, epidemiology, competitive intelligence, macro trends, etc.) to identify growth opportunities, business risks, and emerging portfolio inflection points.
Strengthen Genentech’s ability to anticipate near- and long-term portfolio direction with scenario thinking and predictive forecasting.
Help to build, enhance, and automate the analytical tools and systems supporting portfolio performance and forecasting.
Partner with Digital/DDA teams to leverage AI and advanced analytics (forecasting automation, anomaly detection, scenario modeling, insight generation) to increase speed, accuracy, and scalability.
Help to shape analytics products across Finance, translating stakeholder needs into clear business requirements and ensuring continuous improvement of outputs and user experience.
Help to strengthen the Monthly Outlook process, with a heavy emphasis on forecasting accuracy, forward-looking insights, and executive-level storytelling.
Deliver robust portfolio revenue insights that inform Genentech’s P&L commitments to Roche and enable proactive performance management.
Support the Head of Portfolio Forecasting in shaping the strategic direction and evolution of the overall forecasting and insights service model.
Develop compelling narratives around business performance and outlook, simplifying complexity into clear strategic implications for senior leaders.
Provide recommendations on scenarios, supporting leadership in making informed decisions.
Drive alignment across stakeholders by ensuring a consistent and trusted portfolio story across Finance, Strategy, and Enterprise reporting.
Build and continuously evolve the capabilities required for world-class portfolio analytics: tools, talent, workflows, governance, and operating model.
Mentor and develop analysts and forecasting professionals, strengthening business judgment, data literacy, and modern technical capability.
Proactively assess resourcing needs and flex talent toward the highest-value business priorities.
Lead change efforts to improve portfolio forecasting, simplify analytics workflows, and increase speed and decision usefulness.
Drive cross-organizational opportunities (Genentech/Roche) to improve speed, simplicity, patient-centricity, and effectiveness through insights.
Ensure full compliance with Genentech/Roche policies and all laws and regulations governing business conduct.