Open Rank Laboratory Sciences Professional

University of Colorado•Aurora, CO

1d•Onsite

About The Position

A full-time (1.0 FTE) Laboratory Sciences Professional (Entry or Intermediate) position is available in the field of genomic mosaicism. The research group is located within the Department of Pediatrics, School of Medicine, in the Section of Clinical Genetics and Metabolism. This position will be responsible for performing a broad array of genetic and molecular assays and techniques in the area of genetics, genomics, and molecular biology. This work will be part of essential laboratory support tasks and include experiments performed independently and under the supervision of the principal investigator and other laboratory members. In addition, this position will be responsible for managerial aspects of the Breuss laboratory, support of the Principal Investigator’s (PI) scientific administration (all levels), and the mentoring of junior researchers (Intermediate only). The Breuss laboratory is located in the Department of Pediatrics in the Section of Genetic and Metabolism on the Anschutz Medical Campus. We are part of a thriving research environment and are working at the cutting edge of genome biology and genetic mosaicism.

Requirements

Entry Level: Bachelor’s degree in biology, molecular biology, chemistry, genetics, or related field.
Intermediate Level: Bachelor’s degree in biology, molecular biology, chemistry, genetics, or related field.
One (1) year of professional-level research experience.
Applicants must meet minimum qualifications at the time of hire.
Willingness to work with an array of biological samples, including blood, semen, and postmortem tissues.
Willingness to work with laboratory mice and primary cell culture.
Laboratory management skills.
Willingness to learn about and work with databases, command lines, and scripting languages.
Excellent organizational and documentation skills.
Detail-oriented and responsive.
Ability to collaborate and work effectively in a team environment.
Self-motivated and scientifically inquisitive.
Ability to quickly assess situations, identify solutions, and implement fixes.
Strong interpersonal skills that foster a positive lab culture, professional development, and scientific rigor.
Receptive to feedback and committed to continuous improvement of management practices.
Critical thinking, creativity, and the ability to remain calm under pressure.
Knowledge of basic laboratory techniques, including safety procedures and techniques.
Ability to communicate effectively, both in writing and orally.
Ability to establish and maintain effective working relationships with employees at all levels throughout the institution.
Ability to interpret and master complex research protocol information.

Nice To Haves

Entry Level: Demonstrated experience working in a biomedical research laboratory.
Master’s degree in biology, molecular biology, chemistry, genetics, or related field.
One (1) year of experience in an experimental or wet laboratory.
Laboratory management skills.
Training in working with and organizing human samples.
Training in next-generation sequencing library preparation.
Training in cell culture techniques.
Experience in mentoring students/staff.
Experience working on the command line and the analysis of omics data using scripting languages.
Experience with grant-writing or manuscript-writing (as part of a team or an individual).
Intermediate Level: Master’s degree in biology, molecular biology, chemistry, genetics, or related field
Two (2) years of experience in an experimental or wet laboratory.
Laboratory management skills.
Training in working with and organizing human samples.
Training in next-generation sequencing library preparation.
Training in cell culture techniques.
Experience in mentoring students/staff.
Experience working on the command line and the analysis of omics data using scripting languages.
Experience with grant-writing or manuscript-writing (as part of a team or an individual).

Responsibilities

DNA/RNA preparation from primary human tissues (e.g., blood, saliva, semen, postmortem or surgical tissues), primary cells, or immortalized cell lines.
Standard and advanced molecular biology and genetic techniques, such as molecular cloning, PCR, ddPCR, library preparations, and analytical methods (e.g., gel electrophoresis).
Maintenance and experimentation in cell culture systems, including expansion of cell lines, cryopreservation, and routine mycoplasma testing.
Maintaining a detailed, accurate, and current experimental record.
Data organization and analysis.
Active participation in laboratory meetings and journal clubs.
Drive projects independently (Intermediate only).
Manage daily laboratory operations: ordering and maintaining inventory, keeping organization and cleanliness of equipment and working spaces, preparing reagents, maintaining laboratory records and databases, and ensuring safety and regulatory compliance of the laboratory.
Assist in the review and implementation of lab support policies, practices, and programs to meet organizational, operational, and management needs.
Processing, storage, and tracking of biological specimens.
Coordinate and execute shipping and receiving of biological specimen sampling kits.
Develop, maintain, and revise standard operating procedures.
Anticipate future laboratory needs.
Stay current with technological advances. Coordinate the onboarding process for new laboratory personnel, ensuring proper access and regulatory compliance.
Train onboarding scientists.
Supervise junior scientists.
Coordinate with collaborators.
Supervise junior scientists (Intermediate only).
Assist the principal investigator in the preparation of manuscripts and grant applications.
Support the PI in the financial administration of the laboratory (e.g., expense reports, budgeting, supervision of active financial accounts).