MSL/ Sr. MSL - Central

Centessa Pharmaceuticals, LLC•Houston, TX

2d•$170,000 - $250,000•Remote

About The Position

Centessa Pharmaceuticals plc (Nasdaq: CNTA) new kind of pharmaceutical company with a deconstructed R&D environment that prioritizes data driven decision making led by subject matter experts. Centessa is advancing a portfolio of high conviction programs with strong biological validation. Our asset-centric model offers a unique R&D logic that has been applied by single asset companies to improve productivity. This operating model has minimal centralized infrastructure, reduced hierarchy, and exclusive focus on data driven capital allocation. Our teams are uniquely incentivized to expeditiously interrogate key scientific hypotheses. We believe the asset-centric model can lead to improved success rates for programs with greater speed and modest costs. Description of Role The MSL / Sr. MSL will serve as a field-based scientific expert responsible for engaging with healthcare professionals (HCPs), supporting clinical development, and ensuring alignment with Centessa’s strategic medical objectives. This role is critical in translating complex scientific data into meaningful clinical insights and fostering compliant, evidence-based dialogue with thought leaders.

Requirements

Advanced degree (PhD, PharmD, MD, DO, PsyD, DNP) in life sciences or a related field (from An Accredited College or University).
Minimum of 2 years (4 years for Senior MSL) of experience in a Medical Affairs or MSL role within the pharmaceutical or biotech industry
Exceptional verbal and written communication skills; ability to tailor scientific messages to diverse audiences and ability to interpret and communicate complex scientific data
Proven ability to build and maintain strong relationships with KOLs, investigators, and internal stakeholders
Strong understanding of clinical trial design, regulatory requirements, and therapeutic area landscape
Skilled in developing and delivering scientific presentations in various settings
Strong understanding of industry regulations and guidelines governing medical interactions
Ability to align field activities with broader medical and corporate strategies
Must have a valid driver’s license with a driving record that meets company requirements
Must reside within one of the following metropolitan areas: Chicago, St. Louis, Houston, or Dallas.
Willing and able to travel frequently within assigned territory, which includes: Chicago, Indianapolis, St. Louis, Dallas, Houston.
Senior MSLs have a proven ability to lead and mentor peers

Nice To Haves

Excellent understanding of sleep medicine and associated therapeutic areas is strongly preferred

Responsibilities

Maintain a high level of therapeutic area expertise and scientific knowledge relevant to Centessa’s pipeline and marketed products in alignment with Medical Affairs strategic objectives
Engage in compliant, non-promotional scientific exchange with key opinion leaders (KOLs), investigators, and other HCPs
Serve as a trusted scientific resource to external stakeholders, providing accurate and balanced medical information
Deliver company-approved, high-quality medical/scientific presentations to a variety of audiences including formulary committees and healthcare professionals.
Provide medical/scientific support for critical Centessa activities including speaker training, advisory boards, and sales training as appropriate
Ensure accurate, timely, and compliant documentation of field-based activities in accordance with MSL organization guidelines
Collaborate with Clinical Operations to identify and evaluate potential clinical trial sites and investigators based on scientific expertise, patient population, and alignment with study objectives
Provide scientific education and protocol-specific training to investigators and site staff during site initiation visits, ensuring thorough understanding of study rationale and endpoints
Maintain ongoing engagement with trial sites and investigators to facilitate successful execution of clinical trial objectives, provide ongoing scientific support, address protocol-related inquiries, and ensure high-quality data generation
Attend relevant scientific and medical congresses to stay current with emerging data and trends
Provide real-time insights and post-conference reports to internal teams
Support Centessa’s presence at congresses through development of pre-conference plans, booth coverage, symposia participation, and KOL engagement
Contribute to the development of scientific slide decks, FAQs, and educational materials
Writing and editing Medical Information response letters
Ensure all materials are medically accurate, evidence-based, and compliant with regulatory standards
Collaborate with Medical Affairs and Legal teams to ensure scientific content meets internal and external guidelines
Lead MSL strategic initiatives/projects aligned with Medical Affairs and MSL organization strategy
Develop and implement scientific training plans for the MSL team
Contribute to MSL organization strategy in collaboration with MSL leadership
Mentorship of MSL peers
Senior MSLs will be responsible to leading strategic conference planning, execution, and reporting

Benefits

In addition to base pay, this role is eligible for a discretionary annual bonus and participation in our equity program, allowing you to share in Centessa’s long-term success.
Centessa also offers a comprehensive benefits package, which includes a 401(k) plan, company-sponsored medical, dental, vision, and life insurance, generous paid time off, and a health and wellness program.

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