mRNA Process Development Co-op
About The Position
Beam Therapeutics is a biotechnology company committed to establishing the leading, fully integrated platform for precision genetic medicines. To achieve this vision, Beam has assembled a platform with integrated gene editing, delivery and internal manufacturing capabilities. Beam’s suite of gene editing technologies is anchored by base editing, a proprietary technology that is designed to enable precise, predictable and efficient single base changes, at targeted genomic sequences, without making double-stranded breaks in the DNA. This has the potential to enable a wide range of therapeutic editing strategies that Beam is using to advance a diversified portfolio of base editing programs. Beam is a values-driven organization committed to its people, cutting-edge science, and a vision of providing life-long cures to patients suffering from serious diseases. Beam is looking for a highly motivated Co Op to join our Process Development Team from July to Dec of 2026. The Co Op will assist in development and optimization of linearized plasmid DNA manufacturing processes. Specifically, this role will involve performing and optimizing plasmid isolation, linearization, and chromatographic purification. The ideal candidate for this role is detail-oriented, persistent, and has an innovative mindset toward solving technical challenges. This position will play a central role in developing internal capabilities for plasmid linearization and purification development while providing the individual exposure to one of the most important classes of medication of the 21st century.
Requirements
- Pursuing a BS/MS/PhD in biological sciences or a related field (Bioengineering, Biochemistry/Biophysics, Cell Biology/Molecular Biology, Chemical Engineering) with at least 1 year of relevant laboratory experience.
- Knowledge of biochemical & molecular biology methods used in drug discovery and development.
- Proficient in Excel, PowerPoint, and data analysis.
- Experience maintaining a lab notebook and following written protocols.
- Motivated to learn and detail oriented with excellent organizational and communication skills.
Responsibilities
- Perform laboratory experiments on plasmid DNA isolation, linearization and chromatographic purification.
- Assist optimization of reaction parameters for restriction digestion
- Run analytical methods including capillary electrophoresis, agarose gel electrophoresis, and high-performance liquid-chromatography to analyze the reaction products and interpret data.
- Maintain detailed documentation of experiments in the ELN system.
- Adhere to all laboratory safety requirements and procedures.
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What This Job Offers
Career Level
Intern
