Medical College of Wisconsin
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About The Position
An NIH-funded postdoctoral fellowship in the laboratory of Dr. William Drobyski in the Departments of Medicine and Microbiology and Immunology at the Medical College of Wisconsin that is focused on transplantation immunology and immuno oncology. We have ongoing projects focused on the immunobiology of allogeneic bone marrow transplantation, the pathophysiology of graft versus host disease (GVHD), and cancer immunotherapy. Specific areas of interest include inflammatory cytokine networks that contribute to GVHD, inflammatory cytokine signaling and regulatory pathways that impact the development of tolerance, modulate anti-leukemic responses, and induce pathological damage particularly within select organs such as the gastrointestinal tract and central nervous system, and the harnessing and optimizing of T cell function for cancer immunotherapy using genetically modified mouse models, flow cytometry, q-PCR, RNA-seq, western blot, single cell RNA seq, bioinformatics, and other immunological techniques. We also have a strong record of conducting translational clinical trials in which a post-doctoral fellow could contribute and participate. Recent publications include Journal of Clinical Investigation 2016; 126: 3541-3555, JCI Insight 2017; 2(14): 93726, Haematologica 2018; 103(4): 717-727, Blood 2018; 132(4): 435-447, Nature Communications 2018; 9(1): 5037; Blood 2020; 135(8): 568-581, Blood 2021; 137(9): 1241-1255, Blood Advances 2022; 6(9): 2791-2803; and Haematologica 2023; 108(1): 250-256.
