Manufacturing Manager, Liso-cel CAR-T, Manufacturing Operations

About the position

The purpose of the Manufacturing Manager role is to manage and provide oversight of a Work Centered Team (WCT) whose primary responsibility is the execution of Cell Therapy manufacturing processes. The Manufacturing Manager is responsible to ensure their WCT members maintain a culture of safety, compliance, innovation, and Continuous Improvement within the Manufacturing Operations function. This position reports to Senior Manager, Manufacturing. At Bristol Myers Squibb we are reimagining the future of cell therapy. With our bold ambition, backed by a best-in-the-industry team and long-term commitment, we are leading the way to unlock the full promise of cell therapy as we strive to put more patients on the path to a cure. If you are ready to challenge yourself, accelerate your career, and give new hope to patients, there's no better place than here at BMS with our Cell Therapy team.

Responsibilities

• Leads by example and drives their team to adhere to the BMS values of Inclusion, Accountability, Innovation, Urgency and Passion.
• Is accountable to ensure their WCT members execute the manufacturing of Cell Therapy products according to Current Good Manufacturing Practices (cGMP's) following the current, approved Standard Operating Procedures (SOPs) and Work Instructions (WIs).
• Takes personal responsibility to work safely and to ensure their WCT members do the same.
• Performs regular safety Gemba walks, knows the hazards associated with their work and demonstrates safe behavior.
• Operates and maintains equipment to prevent injuries or incidents.
• Is accountable for the Production Records produced by their WCT members.
• Performs batch record reviews (BRR) or Electronic Batch Record review by exception.
• Ensures that all documentation produced by their WCT members follows the ALCOA+ principles.
• Ensures the documentation produced by their WCT members is right first time and all records and logbooks are complete and accurate.
• Resolve documentation errors and corrections as needed to enforce manufacturing turnaround-times.
• Is required to perform Cell Therapy manufacturing to maintain hands on expert knowledge of each Unit Operation.
• Further develops technical expertise of CAR T Manufacturing requirements.
• Is responsible to provide the Production Scheduling team with information on the availability of their WCT production resources.
• Sets their WCTs priorities and adjusts as necessary to track the site and or functional priorities.
• Reports out performance metrics and goal progress daily, weekly, monthly in functional and site Tier meetings.
• Ensures that their WCTs have the appropriate level of training necessary for CAR-T GMP manufacturing.
• Is responsible to build high performing WCTs comprising of Operators, Team Leads and Supervisors.
• Works proactively to reduce the number of deviations occurring within the WCTs.
• Participates in CAPAs, Change Controls and Projects from time to time as required by the business.
• Effectively controls expenses within their influence.
• Facilitates and leads weekly Tier meetings with their WCT.
• Maintains balanced and unbiased functional relationships, championing a culture of exceptional teamwork and communication across the organization.

Requirements

• Bachelor's degree in related field is preferred, or equivalent in work experience.
• 5+ years of relevant manufacturing experience.
• Minimum of 2 years leadership experience including the management of direct reports required.
• Extensive knowledge of EHS and cGMPs and the know-how to work and manage within a regulated environment.
• Demonstrates aptitude for biotechnology principles and manufacturing systems.
• Demonstrated proficiency in selection of team and effectively managing personnel issues.
• Adaptable to a fast paced, complex, and ever-changing business environment.
• Knowledge of lean manufacturing principles required.
• Excellent communication skills.

Nice-to-haves

• Advanced degree preferred.

Benefits

• Competitive benefits, services and programs that provide resources to pursue goals at work and in personal lives.