Manufacturing Associate

Immatics•Houston, TX

46d•Onsite

About The Position

Join Immatics and shape the future of cancer immunotherapy; one patient at a time! Immatics is committed to making a meaningful impact on the lives of patients with cancer. We are the global leader in precision targeting of PRAME, a target expressed in more than 50 cancers. Our cutting-edge science and robust clinical pipeline form the broadest PRAME franchise with the most PRAME indications and modalities, spanning TCR T-cell therapies and TCR bispecifics. Why Join Us? Innovative Environment: Help to pioneer advancements in cancer immunotherapy. Collaborative Culture: Be part of a diverse team dedicated to your professional growth. Global Impact: Contribute to therapies that make a lasting impact on patients globally. We are seeking Manufacturing Associates of various levels to support our CMC-GMP Manufacturing team. The Manufacturing Associate will be responsible for supporting clinical manufacturing by performing specialized, time-sensitive cell processing and testing procedures on patient-derived cellular products. This role ensures compliance, product integrity, sterility, and accurate documentation in accordance with regulatory and quality standards. Level and scope of responsibility will be determined based on education, experience, and demonstrated technical expertise. FLSA Classification: Hourly, Non-Exempt Schedule: 0800 - 1700 or 1230 - 2100; Monday to Friday; On-site Reports to: Manufacturing Manager Location: 13203 Murphy Road Suite 100 Stafford, TX 77477

Requirements

Manufacturing Associate I Associate degree (or enrollment) in Biology, Biotechnology, Biomanufacturing, or related field 0–2 years of relevant experience
Manufacturing Associate II Associate or Bachelor’s degree in related scientific field 2+ years of GMP or cell therapy manufacturing experience
Senior Manufacturing Associate Bachelor’s degree preferred 4+ years of GMP or cell therapy manufacturing experience Demonstrated technical leadership and advanced troubleshooting capability
Independent Working- routine tasks with limited supervision; non-standard tasks with close supervision.
Communication- clear and efficient verbal and written communication; common courtesy; interaction mainly limited to own team (peers and supervisor)
Problem Solving- ability to identify, deeply analyze and communicate problems; basic ability to develop suitable solutions.
Critical Thinking- basic reflection on standard processes; identification of basic need and room for improvement within own or narrow scope.
Initiative- high degree of initiative and intrinsic motivation to exceed basic expectations of own tasks and responsibilities.
Organizational & Prioritization Skills- basic organization skills required to structure own daily tasks according to predefined work packages, schedule and standard lab processes; prioritization in close interaction with supervisor.
Coachability- receive pre-defined trainings essential for area of responsibility; high responsiveness to constructive criticism and basic ability to autonomously reflect on required improvements; timely implementation of suggested improvements.
Leadership Skills, Training & Supervision- basic leadership skills required for on-the-job trainings and guidance/support of (new) team members (e.g. providing and receiving feedback, empathy, honesty, reliability); train, instruct and coordinate E level; train D & C level during onboarding.
Legal eligibility to work in the United States is required.

Responsibilities

Serve as operator and/or verifier for cell growth and manipulation procedures, including cell enrichment, culture, cryopreservation, thawing, and washing
Perform manufacturing activities in compliance with FDA Good Laboratory Practices (GLP), Good Manufacturing Practices (GMP), Good Tissue Practices (GTP), and standards including FACT, CAP, and CLIA
Adhere to ALCOA++ and cGDocP requirements while maintaining accurate, compliant documentation and batch records
Ensure aseptic handling of reagents and cellular products to maintain sterility and integrity through final patient infusion
Follow strict cleanroom gowning and environmental procedures (Grade A/B/C/D environments)
Identify and document deviations/events, notify leadership and Quality in a timely manner, and support root cause investigations and CAPAs
Work productively in a highly collaborative, creative, and fast-paced manufacturing environment
Independently perform calculations for cell viability, dilutions, and concentrations
Complete required logs, trackers, and documentation accurately
Maintain GMP cleanliness (autoclaving, waste handling, facility organization)
Support donor evaluation knowledge, screening/testing requirements, labeling, product acceptability, and release criteria
Support validation and study activities (IQ/OQ/PQ)
Provide input on change controls, work instructions (WIs), SOPs, deviations, OOS/OOE investigations, reports, and CAPAs
Perform routine equipment maintenance and troubleshooting
Prepare and present manufacturing summaries, as applicable
Demonstrates increased independence, technical proficiency, and ability to serve as verifier; contributes to process improvements and troubleshooting.
May lead manufacturing runs, mentor junior staff, assist with training, and drive continuous improvement initiatives.

Benefits

Competitive rates for Health, Dental, and Vision Insurance
4 weeks of Paid Time off, granted up front each year and prorated for first and last year of employment.
Sick Time Off – 56 hours
12 Paid Holidays
100% Employer-Paid Life Insurance up to at 1x annual salary, up to one hundred thousand (club together)
100% Employer Paid Short- and Long-Term Disability Coverage
401(k) with Immediate Eligibility & company match… You are eligible for 401(k) plan participation as of your first paycheck. The company will match 100% of your contributions up to 3% of your base salary for the first two years of employment, 4% for years 2-3 of employment, and up to 5% of your salary from the fourth year onward of continued employment.
Partially paid Parental Leave for eligible employees. (3 weeks)
Additional voluntary employee paid coverages including Accident, Hospital Indemnity, and Critical Illness
Employee Paid Identity Theft Protection and Pet Insurance.
Opportunities to work with leading experts in the field of T-cell immunotherapy.
Company provided learning and development opportunities
Fast paced, high demand collaborative and dynamic environment.