Revolution Medicines is a clinical-stage precision oncology company focused on developing novel targeted therapies to inhibit frontier targets in RAS-addicted cancers. The company’s R&D pipeline comprises RAS(ON) Inhibitors designed to suppress diverse oncogenic variants of RAS proteins, and RAS Companion Inhibitors for use in combination treatment strategies. As a new member of the Revolution Medicines team, you will join other outstanding Revolutionaries in a tireless commitment to patients with cancers harboring mutations in the RAS signaling pathway. The Opportunity: Serve as Revolution Medicines’ primary business operation lead and project management interface between internal PDM functions and Contract Research Development Manufacturing Organization (CRDMOs) for raw materials, key starting materials, and regulatory starting materials by providing adequate oversight. Establish and maintain mutually beneficial long-term business relations with CRDMOs. Support contract negotiations in close collaboration with SSSM leadership and cross-functional teams (e.g., Subject Matter Experts (SMEs), Finance, and Legal) to ensure best terms and conditions. Support preparation and execution of CRDMOs business reviews with SSSM leadership, PDM senior management, and business counterparts. Support development and implementation of outsourcing strategies for PDM. Support the selection process for CRDMOs in collaboration with SSSM leadership and technical SMEs. Ensure projects/programs meet desired results, compliance, speed, quality, and cost. Support development of scope of work (SOW) in close collaboration with SSSM leadership and technical SMEs. Support cross-functional CRDMO management activities, covering all aspects such as business needs identification, market screening, contracting, vendor qualification and set-up, compliant delivery of services, and discontinuation. Support management of CRDMO budget, purchase orders, and invoices. Work with SSSM leadership, PDM senior management, and cross-functional teams to assess and manage supplier performance through use of personal influence, internal business review meetings, and/or joint governance meetings. Identify and deliver on cost savings opportunities.