Manager, Sample Management

Revolution Medicines • Redwood City, CA

7h • Onsite

About The Position

Revolution Medicines is a clinical-stage precision oncology company focused on developing novel targeted therapies to inhibit frontier targets in RAS-addicted cancers. The company’s R&D pipeline comprises RAS(ON) Inhibitors designed to suppress diverse oncogenic variants of RAS proteins, and RAS Companion Inhibitors for use in combination treatment strategies. As a new member of the Revolution Medicines team, you will join other outstanding Revolutionaries in a tireless commitment to patients with cancers harboring mutations in the RAS signaling pathway.
The Opportunity:
We are seeking a hands-on Manager of Sample Management to lead day-to-day laboratory operations and directly supervise staff within the sample management function. Reporting to the Director of Sample Management, this role is ideal for a working leader who enjoys being shoulder-to-shoulder with their team, actively directing work, troubleshooting issues in real time, and ensuring high-quality execution. The successful candidate will combine strong people leadership with deep operational experience in modern sample and compound management environments.

Requirements

• BS/MS or equivalent degree in chemistry, biology, engineering, or a related scientific discipline.
• 5 years experience in sample management, compound management, or laboratory operations.
• Proven experience directly supervising and leading technical staff in a laboratory environment.
• Hands-on experience with automated sample storage systems, LIMS, and laboratory automation tools.
• Strong attention to detail, operational discipline, and commitment to data integrity.
• A proven background in continuous improvement methodologies.
• Comfort operating in a fast-paced, collaborative discovery environment.
• Clear and effective written and verbal communication skills.

Nice To Haves

• Experience supporting small-molecule drug discovery programs.
• Experience training and mentoring early-career scientists or technicians.
• Exposure to process improvement initiatives or system implementations.
• Familiarity with vendor-managed laboratory automation platforms.
• Direct experience with Cenevo’s Sample Management Software Mosaic.

Responsibilities

• Provide direct, hands-on leadership to sample management staff, including daily work assignment, prioritization, and real-time problem solving.
• Manage and participate in core sample management activities, including sample receipt, storage, tracking, retrieval, and disposal.
• Ensure smooth day-to-day operation of automated storage systems, LIMS, and supporting laboratory infrastructure.
• Train, mentor, and develop staff through on-the-job coaching, feedback, and performance management.
• Implement, maintain, and enforce SOPs and best practices for all critical sample management processes.
• Identify and implement process improvements to enhance efficiency, reliability, and scalability.
• Serve as the primary point of contact for cross-functional partners, ensuring timely and accurate delivery of materials.
• Work closely with the Director of Sample Management to communicate capacity, risks, and resource needs.
• Support onboarding and ramp-up of new staff and technologies within the laboratory.

What This Job Offers

• Job Type: Full-time
• Career Level: Manager