Lab & Research Technician II

State of Virginia•Charlottesville, VA

44d•Onsite

About The Position

Dr. Jarrod Marto of the University of Virginia Department of Biochemistry & Molecular Genetics and Department of Chemistry is recruiting a highly motivated research technician to join his team. This position is an excellent opportunity for those seeking an immersive research experience prior to continuing their career at graduate or medical school. Studies in Dr. Marto's lab are aimed at understanding how genetic mutation or the action of small molecule probes impact the functional proteome, including protein post-translational modifications, biochemical complexes, signaling pathways, or how they manifest en masse as phenotypic or disease signatures. The successful candidate will work closely with senior lab personnel to design and implement experiments to quantify cellular proteins or PTMs as well as to identify on- and off-target binding of small molecule probes at the level of individual proteins, related gene families (e.g., kinases or other enzymes), and proteome-wide. These proteomic and chemical proteomic studies span multiple laboratory activities including tissue culture, extraction and isolation of proteins and peptides, target engagement assays, activity-based protein profiling, biochemical validation assays, and analysis of large-scale mass spectrometry data. As the successful applicant builds skills they will be expected to work with greater independence to execute SOPs across multiple projects; significant contributions of data and analysis will be recognized through laboratory scientific presentations and publications. Successful candidates will present data during lab meetings, accurately document results, work with PI to discuss experiments, assist undergraduate students and volunteers in the lab and work with Professional Research Staff and Research Faculty to facilitate further experimental results. This role provides operational and administrative support under moderate supervision. It also involves planning and conducting experiments, analyzing data, and collaborating with researchers in laboratory settings.

Requirements

Associate's degree required; may accept equivalent combination of experience, education, certification in lieu of degree.
2+ years of lab experience which may include student experience.

Nice To Haves

Bachelor's degree in biology, chemistry, or related field
Hands-on experience in biomedical research techniques, and basic computer skills.
Demonstrated experience in mass spectrometry or other high-throughput molecular profiling techniques as well as python or other scripting languages is a plus but not required.
This opportunity is in a collegial multidisciplinary lab environment; additional requirements for this position include strong interpersonal and organizational skills, attention to detail, methodical record keeping, and a desire to contribute to research projects both independently and within a team.

Responsibilities

Present data during lab meetings
Accurately document results
Work with PI to discuss experiments
Assist undergraduate students and volunteers in the lab
Work with Professional Research Staff and Research Faculty to facilitate further experimental results
Plan and conduct experiments
Analyze data
Collaborate with researchers in laboratory settings