Revolution Medicines is a late-stage clinical oncology company developing novel targeted therapies for patients with RAS-addicted cancers. The company’s R&D pipeline comprises RAS(ON) inhibitors designed to suppress diverse oncogenic variants of RAS proteins. The company’s RAS(ON) inhibitors daraxonrasib (RMC-6236), a RAS(ON) multi-selective inhibitor; elironrasib (RMC-6291), a RAS(ON) G12C-selective inhibitor; zoldonrasib (RMC-9805), a RAS(ON) G12D-selective inhibitor; and RMC-5127, a RAS(ON) G12V-selective inhibitor, are currently in clinical development. As a new member of the Revolution Medicines team, you will join other outstanding professionals in a tireless commitment to patients with cancers harboring mutations in the RAS signaling pathway. The Opportunity: The Translational Sciences Intern will support the Translational Sciences team in advancing programs that connect preclinical discovery with clinical development. This role provides exposure to how Translational Research integrates molecular biology, pharmacology, biomarker discovery, and clinical data to inform therapeutic development in precision oncology. The intern will gain insight into how translational strategies are developed to understand drug mechanisms, identify biomarkers of response and resistance, and guide clinical trial design. This position is ideal for a student interested in translational cancer research and the interface between laboratory science and clinical application. The role focuses on learning, analysis, and cross-functional collaboration within a multidisciplinary drug development environment. This role provides the opportunity to learn some or all the following, depending on project assignments and team needs. How translational research supports the development of targeted therapies in oncology. How biomarker strategies are developed to support clinical trials and precision medicine approaches. • How preclinical data are integrated with clinical observations to understand mechanisms of response and resistance. How cross-functional teams across discovery biology, pharmacology, clinical development, and bioinformatics collaborate in drug development. How experimental and clinical datasets are analyzed and interpreted to generate translational insights. How translational scientists communicate complex scientific findings to multidisciplinary teams.
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Career Level
Intern