Intern- Product Development, Molecular Biodistribution

Asklepios BioPharmaceutical, Inc. (AskBio)Philadelphia, PA
3dOnsite

About The Position

AskBio Inc., a wholly owned and independently operated subsidiary of Bayer AG, is a fully integrated gene therapy company dedicated to developing life-saving medicines and changing lives. The company maintains a portfolio of clinical programs across a range of neuromuscular, central nervous system, cardiovascular, and metabolic disease indications with a clinical-stage pipeline that includes investigational therapeutics for congestive heart failure, limb-girdle muscular dystrophy, multiple system atrophy, Parkinson’s disease, and Pompe disease. AskBio’s gene therapy platform includes Pro10™, an industry-leading proprietary cell line manufacturing process, and an extensive array of capsids and promoters. With global headquarters in Research Triangle Park, North Carolina, and European headquarters in Edinburgh, Scotland, the company has generated hundreds of proprietary capsids and promoters, several of which have entered pre-clinical and clinical testing. Our vision: Pioneering science to create transformative molecular medicines. Our mission: Lead innovative science and drive clinical outcomes to transform people's lives. Our principles: Advance innovative science by pushing boundaries. Bring transformative therapeutics to patients in need. Provide an environment for employees to reach their fullest potential. Our values: Be a Pioneer. We are not afraid of the impossible and to innovate to make gene therapies accessible to those in need. Cultivate Collaboration. Strive to be the best teammate, actively listen, openly communicate, and embrace diverse points of view. Embrace Responsibility. We are humbled by the enormity of our mission. We hold a relentless commitment to advance science and clinical outcomes for our patients, families, and caregivers. Raise the Bar. Continuously drive improvements and efficiencies. Seek and provide constructive feedback. Have a bias for learning and action. Act with Uncompromising Integrity. Be honest, transparent, and committed to doing what’s right in every situation. Make clear commitments and follow through. Position Summary The Intern- Product Development, Molecular Biodistribution will collaborate closely with Biodistribution Core personnel to isolate nucleic acids from mouse tissue samples and carry out PCR/digital PCR using established molecular methodologies. The intern will also help to develop high throughput methods to optimize work for the Core. We are looking for candidates who possess a strong foundation in biology, molecular biology, or biochemistry with a desire to learn and grow. The Intern- Product Development, Molecular Biodistribution is based in Philadelphia and reports to the Senior Scientist, Biodistribution Lead.

Requirements

  • Currently pursuing a BS in Biology, Molecular Biology, Biochemistry, or related field
  • Must be at least a Junior in university at the time of your application
  • Solid foundational understanding of cell biology, genetics, and molecular biology principles
  • Required technical experience with pipetting and prior lab experience with basic techniques (PCR, nucleic acid extraction)
  • Strong sense of accountability and ability to prioritize multiple tasks
  • Excellent organizational skills and attention to detail
  • Excellent verbal and written communication skills
  • Flexible and willing to support a variety of tasks for the (department) team
  • Excellent problem solving skills
  • Available to work full-time at the office during the summer months (May-August) at an AskBio office

Nice To Haves

  • Prior internship or work experience in a similar role

Responsibilities

  • Process mouse tissue samples for DNA/RNA extraction.
  • Conduct high throughput dPCR using project specific primers.
  • Collaborate with team members to develop and implement high throughput molecular workflows.
  • Analyze experimental data, interpret results, and communicate effectively with team members to ensure project goals are met.
  • Learn about different platforms for nucleic acid analysis (nanodrop, Qubit, TapeStation, QIAcuity).
  • Maintain detailed laboratory notebooks and follow Standard Operating Procedures (SOPs).
  • Participate in team meetings and provide updates on project progress.
  • Collaborate with other departments and teams to support cross-functional projects.
  • Follow best practices for data management and analysis.
  • Assist in the preparation of reports and presentations to share research findings.
  • Contribute ideas and suggestions for improving processes and workflows.
  • Adhere to company standards and regulations.
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