Intern-Clinical Immunology

Asklepios BioPharmaceutical, Inc. (AskBio) • Durham, NC

4d • Onsite

About The Position

AskBio Inc., a wholly owned and independently operated subsidiary of Bayer AG, is a fully integrated gene therapy company dedicated to developing life-saving medicines and changing lives. The company maintains a portfolio of clinical programs across a range of neuromuscular, central nervous system, cardiovascular, and metabolic disease indications with a clinical-stage pipeline that includes investigational therapeutics for congestive heart failure, limb-girdle muscular dystrophy, multiple system atrophy, Parkinson’s disease, and Pompe disease. AskBio’s gene therapy platform includes Pro10™, an industry-leading proprietary cell line manufacturing process, and an extensive array of capsids and promoters. With global headquarters in Research Triangle Park, North Carolina, and European headquarters in Edinburgh, Scotland, the company has generated hundreds of proprietary capsids and promoters, several of which have entered pre-clinical and clinical testing. Our vision: Pioneering science to create transformative molecular medicines. Our mission: Lead innovative science and drive clinical outcomes to transform people's lives. Our principles: Advance innovative science by pushing boundaries. Bring transformative therapeutics to patients in need. Provide an environment for employees to reach their fullest potential. Our values: Be a Pioneer. We are not afraid of the impossible and to innovate to make gene therapies accessible to those in need. Cultivate Collaboration. Strive to be the best teammate, actively listen, openly communicate, and embrace diverse points of view. Embrace Responsibility. We are humbled by the enormity of our mission. We hold a relentless commitment to advance science and clinical outcomes for our patients, families, and caregivers. Raise the Bar. Continuously drive improvements and efficiencies. Seek and provide constructive feedback. Have a bias for learning and action. Act with Uncompromising Integrity. Be honest, transparent, and committed to doing what’s right in every situation. Make clear commitments and follow through. Position Summary The intern will contribute to key projects within the Clinical Immunology team, focusing on improving consistency and supporting immunological research. This role offers hands-on experience with laboratory techniques and data analysis, as well as exposure to cross-functional collaboration. The intern will focus on the following projects Project 1: Compare the parameters and performance of analytical lab instruments (e.g. fluorescent cell counter) between two lab locations to ensure alignment within an acceptable range for downstream analytical T cell assay testing. Project 2: Perform cytokine testing on supernatant samples collected from T cell assays to support immunological understanding of AAV. The intern will receive comprehensive training on both cell counting and supernatant testing before executing these projects. At the end of the program, the intern will present findings and recommendations to the Clinical Immunology team. This work will help standardize processes across sites and provide valuable insights into immune responses, contributing to the advancement of clinical programs. The intern will report to a Scientist on the Clinical Immunology team. This position is based at the RTP site.

Requirements

• Must be pursuing a Bachelor’s degree in Biology, Biomedical Engineering, Molecular Biology, Pre-Health
• Must be at least a Sophomore in university at the time of your application
• Strong sense of accountability, ability to prioritize multiple tasks, and curiosity for science
• Excellent organizational and communication skills and attention to detail
• Flexible and willing to support a variety of tasks for the Clinical Immunology team
• Proactive and solution-driven mindset
• Strong sense of accountability and ability to prioritize multiple tasks
• Excellent organizational skills and attention to detail
• Available to work full-time at the office during the summer months (May-August) at an AskBio office

Nice To Haves

• Prior internship, work, or volunteer/extracurricular experience
• Prior experience working in a lab environment that involves skills in pipetting and dilutions

Responsibilities

• Learn about adeno-associated virus (AAV) gene therapy and understand the role of Clinical Immunology in the AAV pipeline.
• Partner with analysts and scientists in the Clinical Immunology group to gain hands-on experience in immunological assays and data interpretation.
• Observe and evaluate clinical program results, including immune response data related to AAV therapies.
• Participate in laboratory activities, including MSD assays, and attend Clinical Immunology team meetings to understand workflows and decision-making processes.
• Assist with supernatant and cell counter testing
• Maintain accurate records of experimental procedures and results in compliance under Good Clinical Laboratory Practices (GCLP)
• Communicate effectively with team members regarding project progress and findings.
• Present summarized findings and observations to the Clinical Immunology team at the conclusion of the internship

What This Job Offers

• Job Type: Full-time
• Career Level: Intern
• Number of Employees: 501-1,000 employees