Under the direction of the department leadership, the Medical Laboratory Scientist II is responsible for Immunohematology Reference Laboratory (IRL) processes according to cGMP compliant policies and Standard Operating Procedures (SOP) implemented by the San Diego Blood Bank (SDBB). The IRL is a highly regulated laboratory where employees must successfully complete/pass an initial training program and complete competency assessments in intervals defined by SDBB policies.. Responsibilities Performs all assigned duties in compliance with internal SOPs and external regulations. Provides guidance and expertise for the laboratory to meet the needs of SDBB customers, in accordance with accepted standards and regulations. Supports the SDBB safety, GMP and Quality Plan. Adheres to GMP guidelines. Assist in training new personnel and other staff members. Assists in the care, maintenance and quality control of equipment and supplies. Maintains department records, reports and statistical data as required. Assists in developing new lab processes and procedures. Assists with laboratory quality and variance programs. Participates in department meetings and educational programs. Interpersonal skills to establish and maintain professional relationships. Decision making skills. Professional communication both written and oral, which is clear and precise. Must be detail oriented, well organized and display good time management skills. Self-motivated and capable of independent work. Integrity and discretion – ability to maintain confidentiality. Ability to perform under pressure and work under stressful situations. Team orientation. Teaching and training abilities. Understands and adheres to the policies, procedures and standards developed as part of the San Diego Blood Bank Compliance Program. Participates in the IRL on call rotation and weekend work rotation. Performs red cell blood grouping and antibody identification on donor and referred patient blood samples. Determines suitability for transfusion of donor units with discrepant ABO or Rh groups and unexpected red cell antibodies. Performs pre-transfusion compatibility testing as needed. Performs platelet crossmatching. Performs adsorptions as needed. Identifies antibodies to high and low prevalence antigens. Identifies autoantibodies. Performs donor and patient red cell antigen typing. Performs elution as needed. Enzyme treats red blood cells as needed. Able to use reducing agents. Able to remove immunoglobulin from red cells as needed. Able to perform inhibition/neutralization testing. Able to perform titrations. Able to identify cold-reactive antibodies. Provides verbal and written reports, technical assistance, and consultation to customers. Performs DNA extractions. Performs Next Generation Sequencing. Investigates and reviews non-conformances through quality incident reporting. Performs supervisory reviews and tasks as needed. Performs validations and new process development. Performs controlled document writing and revisions. Performs other related duties as assigned or requested. Assists with staff training and competency when applicable. May cross train in the Quality Control Laboratory.