HSC Formulation Advisor
About The Position
At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We’re looking for people who are determined to make life better for people around the world. Come join the rapidly expanding Eli Lilly Gene Therapy Team! We are responsible for inventing, characterizing, and advancing novel gene therapy reagents for a myriad of clinical applications. Our team works cross-functionally within our organization across multiple disease areas and platforms. Our goal is to deliver on the promise of gene therapy to patients around the world. This role may require up to 10-15% travel for conferences or training and will include the opportunity to mentor and train two junior scientists. The position is located at 15 Necco St, Boston MA 02210. Full time (40 hours/week). To apply, submit resume via this site.
Requirements
- PhD with 0-3+ years of related experience OR BS/MS with 5+ years of related experience
Nice To Haves
- Strong background in HSC biology and formulation, including flow cytometry, qPCR, ddPCR and related technologies
- Experience with automation and NGS library prep is a plus
- Experience with handling NGS data a plus
Responsibilities
- Formulation and characterization of nanoparticle platforms for nucleic acid delivery (e.g. Electrophoresis, DLS, HPLC, etc.)
- In vitro evaluation of nucleic acid formulation, including expertise on cellular receptors and targeting (e.g. mammalian cell culture, transfection, receptor density and internalization, etc)
- Act as a SME in the HSC targeting space cross-functionally, and openly communicate with necessary teams
- Development of actively targeted nanoparticle platform, including target receptor identification/selection in the context of receptor biology, target engagement and receptor internalization kinetics; ligand selection/curation; particle decoration and related characterization techniques.
- Perform R&D on novel assays to bring in new technologies to the broader team
Benefits
- Full-time equivalent employees also will be eligible for a company bonus (depending, in part, on company and individual performance).
- In addition, Lilly offers a comprehensive benefit program to eligible employees, including eligibility to participate in a company-sponsored 401(k); pension; vacation benefits; eligibility for medical, dental, vision and prescription drug benefits; flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts); life insurance and death benefits; certain time off and leave of absence benefits; and well-being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities).
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What This Job Offers
Job Type
Full-time
Career Level
Mid Level
Education Level
Ph.D. or professional degree
