Histology Specialist

University of North Carolina at Chapel Hill • Chapel Hill, NC

85d

About The Position

The Histology Specialist will become familiar with all aspects of working in the Pathology Services Core. These duties include, but are not limited to, image acquisition, data extraction and analysis, image quality assurance, and implementation of new data software, and maintenance of the imaging database Maintenance of the imaging database requires the constant update of user information to ensure that the proper people have access to the database. The specialist will work directly with customers to design and create data analysis techniques, such as creating macros, to further their experiments. Additionally, the specialist must have the ability to troubleshoot equipment issues that might cause delays in the progress of experiments. Will occasionally need to train and educate core personnel and PIs on new techniques, software, and equipment, as well as providing guidance to work study students working in the lab. They will perform routine and higher-level histopathology and spatial biology tasks. Standard histology testing includes grossing, cassetting, processing/embedding, sectioning, de-identification of samples as needed, H&E staining and special stains. The specialist will complete higher level laboratory experiments such as immunohistochemistry (IHC), immunofluorescence (IF), in situ hybridization (FISH/ISH), multiplex assays, and their respective whole slide imaging using digital pathology equipment. In addition, they will also be responsible for completing sophisticated spatial omics experiments, combining automated biochemistry protocols, wet bench titration processes, while operating spatial omics equipment including appropriate imaging and complementary assays. This includes optimization of all high-level protocols to meet experiment needs. They will work with the client on the details of their project to maximize the amount of information obtained from histology and spatial omics experiments. They will work to keep equipment in functional conditions according to manufacturer guidelines as well as maintain the lab and working areas organized. The applicant will also be responsible for unboxing new materials, keeping track of required consumables for experiment success, and placing needed materials on the order list or following alternative processes.

Requirements

• Bachelor's degree in a discipline related to the area of assignment; or equivalent combination of training and experience. All degrees must be received from appropriately accredited institutions.
• Histology and Digital Pathology experience is required. This experience includes cassette printing, processing, embedding, microtome sectioning, standard staining, special staining, IHC, and IF.
• Position requires constant attention to detail.
• General laboratory experience is mandatory, with emphasis on handling chemicals.
• Familiarity with animal physiology and tissue identification is also required.

Nice To Haves

• Preferred candidate will have knowledge in the biological sciences or Histotechnician/Histotechnologist certification or completion of Histology program.
• Strong communication skills, ability to work independently and work with others, and command of written and spoken English.
• Experience in Digital Pathology slide scanning and image analysis is preferred.

Responsibilities

• Image acquisition
• Data extraction and analysis
• Image quality assurance
• Implementation of new data software
• Maintenance of the imaging database
• Design and create data analysis techniques
• Troubleshoot equipment issues
• Train and educate core personnel and PIs on new techniques, software, and equipment
• Provide guidance to work study students working in the lab
• Perform routine and higher-level histopathology and spatial biology tasks
• Complete higher level laboratory experiments such as immunohistochemistry (IHC), immunofluorescence (IF), in situ hybridization (FISH/ISH), multiplex assays, and their respective whole slide imaging using digital pathology equipment
• Responsible for completing sophisticated spatial omics experiments, combining automated biochemistry protocols, wet bench titration processes, while operating spatial omics equipment including appropriate imaging and complementary assays
• Optimization of all high-level protocols to meet experiment needs
• Work with the client on the details of their project to maximize the amount of information obtained from histology and spatial omics experiments
• Work to keep equipment in functional conditions according to manufacturer guidelines as well as maintain the lab and working areas organized
• Responsible for unboxing new materials, keeping track of required consumables for experiment success, and placing needed materials on the order list or following alternative processes

Benefits

• University employees can choose from a wide range of professional training opportunities for career growth, skill development and lifelong learning and enjoy exclusive perks for numerous retail, restaurant and performing arts discounts, savings on local child care centers and special rates on select campus events.
• UNC-Chapel Hill offers full-time employees a comprehensive benefits package, paid leave, and a variety of health, life and retirement plans and additional programs that support a healthy work/life balance.

What This Job Offers

• Job Type: Full-time
• Career Level: Mid Level
• Industry: Educational Services
• Number of Employees: 11-50 employees