Head of R&D Asset Transition & Integration Office (RATIO)

Takeda • Boston, MA

20d • Hybrid

About The Position

At Takeda, we are guided by our purpose of Better Health for People, Brighter Future for the World and our commitment to patients, our people and the planet. As we continue to evolve our portfolio through acquisitions, partnerships, and divestitures, the ability to transition and integrate assets seamlessly is essential to delivering on our commitments to patients, regulators, and partners. We are seeking an Executive Director, Head of R&D Asset Transition & Integration Office (RATIO) to lead and scale a strategic capability at the center of R&D operations. This role is responsible for ensuring that all R&D asset transitions—whether integrations, divestments, or wind-downs—are executed with rigor, predictability, and operational excellence. You will operate at the intersection of science, operations, and strategy—bringing structure to complex transitions while maintaining the highest standards of quality, compliance, and data integrity.

Requirements

• Deep understanding of end-to-end R&D processes, including clinical development, regulatory, safety, and quality systems
• Proven experience leading integration, divestment, or large-scale program management initiatives within a pharmaceutical or biotech environment
• Strong knowledge of data and records management, including regulatory data transfer, system transitions, and archival strategies
• Experience translating complex contractual, regulatory, and scientific requirements into actionable operational plans
• Familiarity with global R&D systems and infrastructure, and how they interact during transitions
• Demonstrated ability to lead in a global, matrixed organization, influencing across functions and regions
• Strong communicator with the ability to simplify complex topics and drive alignment
• Track record of building and developing high-performing teams
• Ability to navigate ambiguity and drive progress, even in highly complex environments
• Commitment to fostering an inclusive, collaborative culture
• Bachelor’s degree in a scientific or related field required; advanced degree (MBA, PhD, MD) preferred
• 12+ years of relevant experience in the pharmaceutical or biotech industry, including R&D operations, program management, or integration/divestment activities.
• Demonstrated leadership in global matrix environments.

Nice To Haves

• Experience in M&A integration/divestment within R&D is preferred.

Responsibilities

• Lead and evolve the RATIO function, overseeing end-to-end execution of R&D asset transitions across integrations, asset wind-downs, divestments, and externalizations
• Drive strategy and execution for complex, global transformation programs—ensuring delivery against timelines, quality standards, and regulatory requirements
• Establish and scale standardized frameworks (tools, ways of working and operating models) to enable repeatable and efficient transition execution
• Oversee critical transition activities, such as TSA support, data transfers, and system decommissioning, etc.
• Partner cross-functionally with stakeholders across R&D, including Business Development, Therapeutic Area Units, Regulatory Affairs, Pharmacovigilance, Quality, IT, and Supply Chain, to align priorities and execution plans
• Ensure compliance and integrity across all transitions, including contractual obligations, regulatory requirements, safety commitments, and data governance
• Provide strategic insights to senior leadership, including risk assessments, resourcing plans, and progress updates
• Drive continuous improvement, incorporating lessons learned to enhance future transition models, capabilities and ways of working
• Maintain organizational readiness to support evolving portfolio strategies, including new acquisitions, asset wind-downs and divestments

Benefits

• U.S. based employees may be eligible for short-term and/ or long-term incentives.
• U.S. based employees may be eligible to participate in medical, dental, vision insurance, a 401(k) plan and company match, short-term and long-term disability coverage, basic life insurance, a tuition reimbursement program, paid volunteer time off, company holidays, and well-being benefits, among others.
• U.S. based employees are also eligible to receive, per calendar year, up to 80 hours of sick time, and new hires are eligible to accrue up to 120 hours of paid vacation.

What This Job Offers

• Job Type: Full-time
• Career Level: Executive
• Number of Employees: 5,001-10,000 employees