Head of Project Toxicology

Evotec

8d • Hybrid

About The Position

As the VP, Head of Project Toxicology, you will define and lead the safety assessment strategy across Evotec drug discovery and development portfolio, ensuring robust, science‑driven decision‑making from early concept through regulatory submission. Serving as the key interface between discovery and development safety, you will shape the direction of our programs, strengthen strategic partnerships, and foster high‑impact collaboration across diverse modalities and therapeutic areas. You will lead and develop a high‑performing team of toxicology experts while working closely with senior leaders across the organisation and our global partners to deliver integrated, forward‑looking safety strategies. This role may be based at any of our global sites, with flexible working arrangements available. Evotec is a life science company with a unique business model that delivers on its mission to discover and develop highly effective therapeutics and make them available to the patients. The Company’s multimodality platform comprises a unique combination of innovative technologies, data and science for the discovery, development, and production of first-in-class and best-in-class pharmaceutical products. Evotec leverages this “Data-driven R&D Autobahn to Cures” for proprietary projects and within a network of partners including all Top 20 Pharma and over 800 biotechnology companies, academic institutions, as well as other healthcare stakeholders. Evotec has strategic activities in a broad range of currently underserved therapeutic areas, including e.g. neurology, oncology, as well as metabolic and infectious diseases. Within these areas of expertise, Evotec aims to create the world-leading co-owned pipeline for innovative therapeutics and has to-date established a portfolio of more than 200 proprietary and co-owned R&D projects from early discovery to clinical development. Evotec operates globally with more than 5,000 highly qualified people. The Company’s 17 sites offer highly synergistic technologies and services and operate as complementary clusters of excellence. For additional information please go to www.evotec.com and follow us on X/Twitter @Evotec and LinkedIn. Please click on the link below to access and review our Privacy Information for Applicants: Privacy Information for Applicants

Requirements

• Extensive senior‑level experience in Toxicology, gained within biotech, pharma, and/or CRO environments, with a strong understanding of the strategic and operational demands of project‑driven organisations.
• Demonstrated leadership of interdisciplinary, cross‑functional teams, with the ability to influence, motivate, and align diverse scientific and operational groups within a complex matrix setting.
• Exceptional communication and scientific synthesis skills, capable of integrating complex data to deliver clear, actionable, and risk‑balanced recommendations to project teams, partners, and senior leadership.
• Proven track record of advancing programs from preclinical discovery into clinical development, across multiple modalities and therapeutic areas.
• Deep expertise in preclinical drug discovery models, with the ability to synthesise complex scientific strategies, navigate uncertainty, and align preclinical plans with development objectives.
• Highly skilled in managing challenging stakeholder dynamics, resolving conflict, and ensuring effective collaboration across discovery, clinical, regulatory, and operational functions.
• Demonstrated experience in preparing and contributing to successful IND/CTA submissions for both small‑molecule and biologic programs.
• Comprehensive knowledge of global regulatory safety guidelines, and their practical application across different modalities and therapeutic landscapes.
• Strong organisational and planning capabilities, with meticulous attention to detail and effective time‑management skills in a fast‑paced environment.
• Creative, strategic problem‑solver with a growth mindset, demonstrating adaptability, curiosity, and an openness to new approaches and emerging science.
• BSc, MSc, or PhD in Toxicology, Pharmacology, Biology, or a related scientific discipline, with substantial relevant experience.

Nice To Haves

• DBAT, ERT, UKRT or equivalent professional certification is desirable

Responsibilities

• Own and advance the organisation’s safety strategy for both internal programs and external partnerships, ensuring Evotec’s toxicology framework remains innovative, data‑driven, and scientifically robust.
• Inspire, mentor, and develop a team of expert toxicologists, providing strong scientific leadership, strategic direction, and a culture of continual learning.
• Provide pivotal support to Discovery teams across small‑ and large‑molecule programs, expertly guiding safety strategy from Target Safety Assessment through Development Candidate (DC) nomination.
• Serve as a trusted subject matter expert to Discovery and Development teams, enabling effective design, execution, and interpretation of regulatory toxicology studies in support of Phase 1 clinical trials and beyond.
• Build and maintain collaborative, trusted relationships with global clients, aligning on safety strategy and ensuring seamless, shared progress toward program objectives.
• Work closely with colleagues across internal functions to foster strong integration, transparent communication, and cohesive decision‑making across the portfolio.
• Model and cultivate a culture of ownership, trust, accountability, and empowerment across the team and broader organisation.

What This Job Offers

• Job Type: Full-time
• Career Level: Executive
• Education Level: Ph.D. or professional degree