Head of Biology

Third Rock VenturesSan Francisco, CA
336d

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About The Position

We are a pioneering biotech company focused on combining large-scale human genetic data with a deep understanding of metabolism and adipocyte biology to develop first-in-class treatments targeting critical and unaddressed drivers of cardiometabolic diseases. Our lead program, MAR001, is a monoclonal antibody that targets ANGPTL4, a protein highly expressed in adipose tissue. MAR001 is designed to lower remnant cholesterol and improve adipose tissue function, offering therapeutic benefits for conditions such as cardiovascular disease and type 2 diabetes. With strong Phase 1 results, MAR001 is currently in Phase 2 clinical development for adults with metabolic dysfunction. In addition, we are advancing multiple undisclosed discovery programs leveraging robust human genetics and validated targets.

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