Head, Global Clinical Science & Medical Affairs for Marketed Products

Takeda • Cambridge, MA

1d

About The Position

OBJECTIVES/PURPOSE : Provide global end-to-end medical and clinical science strategic leadership for marketed products, integrating post-approval clinical development, post-marketing commitments, and medical affairs into a single, cohesive strategy. Ensure robust scientific, clinical, and medical oversight across the lifecycle of marketed products, safeguarding benefit–risk, patient safety, and regulatory compliance globally. Marketed Products portfolio comprised of 31 products with global activities split over 15 Global Program Teams and 80 established brands spanning multiple therapeutic areas. Lead and develop a global organization of physicians, medical affairs leaders, and scientific directors, enabling high-quality scientific & medical strategy and planning, decision-making, execution, and talent development. A senior medical and clinical leader for marketed products, partnering with R&D, Regulatory, Safety, Strategy & Portfolio Division, & Commercial Business Units. Core member of the Marketed Products Medical & Development Leadership Team and chairs the Clinical Review Board for marketed products.

Requirements

• MD required; PhD or equivalent advanced scientific degree strongly preferred.
• Extensive experience in clinical development and medical affairs within the pharmaceutical or biotechnology industry.
• Track record of successful leadership, management, and development of a globally dispersed team of clinical scientists and medical affairs leaders.
• Strong judgement of talent with the ability to make tough talent decisions.
• Deep understanding of global regulatory, safety, and post-marketing requirements.
• Experience in multiple therapeutic areas including oncology
• Demonstrated success influencing senior governance bodies and cross-functional leadership teams as well as the ability to successfully influence and negotiate outside of the organization
• Track record of building high-performing, diverse, and inclusive global teams.
• Stays up to date on emerging technologies and AI advancements and appropriately leverages/implements digital tools, including AI, to enhance productivity and improve efficiency
• Leadership: Embraces and demonstrates a diversity, equity and inclusion mindset and role models these behaviors for the organization
• Engaged and inspiring people manager who invests time in supporting their employees
• Demonstrated ability to work successfully across functions, regions and cultures
• Functional level leadership with the ability to inspire, motivate and drive results
• Excellent communicator, able to persuasively convey both ideas and data, verbally and in writing
• Proven skills as an effective team player who can engender credibility and confidence within and outside the company
• Ability to distil complex issues and ideas down to simple comprehensible terms
• Demonstrates leadership presence and confidence
• Builds teams across functions and geographies with individuals who have the right skills and experience to deliver on key organizational initiatives.
• As a role model leader, invests time in helping others to enhance their skills and perform at a higher level across the organization
• Decision making responsibilities: Provide input to highly complex decisions that impacts development and/or medical affairs
• Accountable for decision making for Clinical Science/Medical Affairs
• Ability to seek diverse input from multiple constituents and stakeholders to drive innovative solutions
• Ability to incorporate feedback and ensure decisions are implemented swiftly to yield flawless execution

Nice To Haves

• PhD or equivalent advanced scientific degree strongly preferred.

Responsibilities

• Accountable for global clinical science and medical affairs strategic oversight for a diverse and large portfolio of marketed products, spanning post-marketing clinical development, lifecycle management, as well as medical affairs activities for a defined portfolio of products.
• Lead the global clinical science and medical affairs organization responsible for marketed products, ensuring scientific rigor, strong medical governance and robust strategic contributions to Global Program Teams (GPTs), Clinical Sub-teams (CSTs) and Medical Strategy Teams (MSTs)
• Oversee clinical development plans, post-marketing commitments, Phase IIIb/IV studies, registries, and real-world evidence generation in alignment with product strategies.
• Ensure benefit–risk assessments, safety evaluations, and clinical components of regulatory submissions are of the highest quality and aligned with global regulatory expectations.
• Provide strategic leadership oversight for global medical affairs strategies, including scientific communications, publications, congress strategy, evidence generation, and external engagement.
• Chairperson for Marketed Products Clinical Review Board and serves as a senior medical representative in scientific governance forums (e.g., Safety Board, labeling oversight, senior scientific committees).
• Partner closely with Patient Safety & Pharmacovigilance, Regulatory Affairs, Clinical Operations, Statistics, Global Project Management, and Business Units, & Commercial to resolve complex scientific or strategic issues.
• Ensure effective transition of assets from R&D Therapeutic Area Units and Global Medical Therapeutic Areas into Marketed Products Medical and Development maintaining continuity of scientific knowledge and business continuity.
• Lead talent development, succession planning, and organizational capability building across global clinical sciences and medical affairs.
• Represents the company externally with health authorities, key opinion leaders, patient advocacy groups, and scientific organizations, ensuring compliant and impactful engagement.
• Collaborates with Legal, Compliance and Regulatory functions to ensure proper and ethical interactions between Marketed Products Medical & Development personnel and external stakeholders.
• Ability to lead the application of AI tools, internal digital platforms and new technological skills to streamline processes, enhance quality & speed

Benefits

• U.S. based employees may be eligible to participate in medical, dental, vision insurance, a 401(k) plan and company match, short-term and long-term disability coverage, basic life insurance, a tuition reimbursement program, paid volunteer time off, company holidays, and well-being benefits, among others.
• U.S. based employees are also eligible to receive, per calendar year, up to 80 hours of sick time, and new hires are eligible to accrue up to 120 hours of paid vacation.

What This Job Offers

• Job Type: Full-time
• Career Level: Executive
• Education Level: Ph.D. or professional degree