Group Leader, Principal Scientist, Antibody Engineering

Genentech • South San Francisco, CA

302d • $143,200 - $265,900

About The Position

We are seeking a talented Principal Scientist (Group Leader) to join the Department of Antibody Engineering in Genentech Research and Development (gRED), where we discover and engineer life-changing antibody drugs through pioneering science and technology. The successful candidate will lead a group to collaboratively develop bi/multi-specific antibodies by building new technologies and workflows to advance future internal antibody drug discovery programs and identify lead clinical candidates.

Requirements

• Ph.D. in a biological science plus post doc experience, including at least 4 years of recent protein engineering and/or antibody engineering in academia, biotechnology and/or pharma
• Strong background in protein engineering, molecular biology techniques, and/or structural biology
• Solid record of accomplishments and publications as evidence of scientific knowledge
• Deep commitment to working as part of teams
• Strong communication and leadership skills

Nice To Haves

• Experience with engineering bi- or multi-specific antibody/protein formats
• Experience with structure-based protein analysis

Responsibilities

• Engage with therapeutic areas to design and apply new antibody MOAs at the interface of biology and molecular engineering
• Leverage structure-based engineering and internal AI/ML capabilities to design novel molecule formats
• Serve as molecule or project team leader to direct therapeutic antibody lead selection, optimization, and engineering to develop best- or first-in-class antibody therapeutics

Benefits

• Relocation benefits available
• Discretionary annual bonus based on individual and Company performance

What This Job Offers

• Job Type: Full-time
• Career Level: Senior
• Industry: Chemical Manufacturing
• Education Level: Ph.D. or professional degree