Genomics Data & Analysis Lead

Sonic Healthcare USA•Woodcliff Lake, NJ

About The Position

We're not just a workplace - we're a Great Place to Work certified employer! Proudly certified as a Great Place to Work, we are dedicated to creating a supportive and inclusive environment. At Sonic Healthcare USA, we emphasize teamwork and innovation. Check out our job openings and advance your career with a company that values its team members! LOCATION: Woodcliff Lake, NJ FULL TIME: Benefits Eligible In this role, you will: Perform primary hands-on genomic data analysis for PCR and NGS-based assays, including quality assessment, variant detection, annotation, and clinical interpretation of somatic and germline variants in accordance with ACMG/AMP, AMP/ASCO/CAP, and institutional guidelines. Review and interpret sequencing data, ensuring accuracy, completeness, and consistency of reported results. Troubleshoot complex or discordant genomic findings and provide expert-level resolution. Validate, optimize, and implement analytical pipelines, software tools, and workflows for molecular diagnostics. Establish and maintain standardized data interpretation criteria and reporting language. Ensure analysis workflows meet defined performance metrics and turnaround time expectations. Develop, document, and maintain SOPs related to genomic data analysis, interpretation, and reporting. Participate in analytical validation studies including limit of detection (LOD), accuracy, precision, reproducibility, and performance verification. Oversee analytical quality control and contribute to Quality Assurance and Quality Improvement programs. Monitor analytical performance trends and implement process improvements as needed. Maintain comprehensive documentation and version control for analytical workflows. Serve as the subject matter expert for genomic data analysis within the laboratory. Support the design and implementation of the future molecular analysis structure and staffing model. Recruit, build, and lead the Molecular/Genomics Analysis team as the laboratory scales. Collaborate with laboratory leadership in defining long-term analytical strategy and infrastructure needs. Ensure genomic data analysis activities comply with CAP, CLIA, NYSDOH, NYS CLEP, and applicable regulatory standards. Participate in audit preparation and responses related to analytical processes. Maintain data security and confidentiality in compliance with HIPAA and institutional policies. Communicate effectively with molecular technologists, pathologists, and laboratory leadership to support case resolution and workflow efficiency. Generate analytical performance reports and quality metrics as required (weekly, monthly, quarterly). Participate in continuing education and professional development activities. Perform other duties as assigned by the Molecular Operations Director. All you need is: MD or PhD in Genetics, Molecular Biology, Bioinformatics, Computational Biology, or related field (Master’s degree with ≥5 years of clinical genomics experience may be considered). Minimum of 3 years of hands-on experience in clinical NGS data analysis and variant interpretation in a CLIA/CAP-accredited laboratory. Strong understanding of regulatory and accreditation requirements (CAP, CLIA, NYS CLEP, FDA if applicable). Excellent communication skills and ability to collaborate effectively within a multidisciplinary diagnostic environment. The above job description is not intended to be an all-inclusive list of duties and standards of the position. Incumbents will follow any other instructions, and perform any other related duties, as assigned by their supervisor.

Requirements

MD or PhD in Genetics, Molecular Biology, Bioinformatics, Computational Biology, or related field (Master’s degree with ≥5 years of clinical genomics experience may be considered).
Minimum of 3 years of hands-on experience in clinical NGS data analysis and variant interpretation in a CLIA/CAP-accredited laboratory.
Strong understanding of regulatory and accreditation requirements (CAP, CLIA, NYS CLEP, FDA if applicable).
Excellent communication skills and ability to collaborate effectively within a multidisciplinary diagnostic environment.

Responsibilities

Perform primary hands-on genomic data analysis for PCR and NGS-based assays, including quality assessment, variant detection, annotation, and clinical interpretation of somatic and germline variants in accordance with ACMG/AMP, AMP/ASCO/CAP, and institutional guidelines.
Review and interpret sequencing data, ensuring accuracy, completeness, and consistency of reported results.
Troubleshoot complex or discordant genomic findings and provide expert-level resolution.
Validate, optimize, and implement analytical pipelines, software tools, and workflows for molecular diagnostics.
Establish and maintain standardized data interpretation criteria and reporting language.
Ensure analysis workflows meet defined performance metrics and turnaround time expectations.
Develop, document, and maintain SOPs related to genomic data analysis, interpretation, and reporting.
Participate in analytical validation studies including limit of detection (LOD), accuracy, precision, reproducibility, and performance verification.
Oversee analytical quality control and contribute to Quality Assurance and Quality Improvement programs.
Monitor analytical performance trends and implement process improvements as needed.
Maintain comprehensive documentation and version control for analytical workflows.
Serve as the subject matter expert for genomic data analysis within the laboratory.
Support the design and implementation of the future molecular analysis structure and staffing model.
Recruit, build, and lead the Molecular/Genomics Analysis team as the laboratory scales.
Collaborate with laboratory leadership in defining long-term analytical strategy and infrastructure needs.
Ensure genomic data analysis activities comply with CAP, CLIA, NYSDOH, NYS CLEP, and applicable regulatory standards.
Participate in audit preparation and responses related to analytical processes.
Maintain data security and confidentiality in compliance with HIPAA and institutional policies.
Communicate effectively with molecular technologists, pathologists, and laboratory leadership to support case resolution and workflow efficiency.
Generate analytical performance reports and quality metrics as required (weekly, monthly, quarterly).
Participate in continuing education and professional development activities.
Perform other duties as assigned by the Molecular Operations Director.