FSP Scientist: Chromatography and Filtration

Thermo Fisher ScientificWorcester, MA
1d$30 - $50

About The Position

Join us as a Scientist! At Thermo Fisher Scientific, you’ll discover meaningful work that makes a positive impact on a global scale. Join our colleagues in bringing our Mission to life - enabling our customers to make the world healthier, cleaner and safer. We provide our teams with the resources needed to achieve individual career goals while taking science a step beyond through research, development and delivery of life-changing therapies. With clinical trials conducted in 100+ countries and ongoing development of novel frameworks for clinical research through our PPD clinical research portfolio, our work spans laboratory, digital and decentralized clinical trial services. Your determination to deliver quality and accuracy will improve health outcomes that people and communities depend on – now and in the future. Our PPD® Laboratory Services team has a direct impact on improving patient health through the expertise of scientists, industry thought-leaders and therapeutic experts. As the world leader in serving science, our laboratory professionals bring their commitment to accuracy and quality to deliver groundbreaking innovations. As a Scientist, your role will be to perform advanced diagnostic testing and analysis, ensure the accuracy and reliability of laboratory results, troubleshoot complex technical issues, and contribute to the continuous improvement of lab procedures and quality standards. Job Description: This position is in the Biologics Purification Development team of the Product Development Science & Technology department at AbbVie Bioresearch Center. The candidate will be involved with all aspects of protein purification and protein chemistry to support biopharmaceutical process development.

Requirements

  • Bachelor's degree or equivalent and relevant formal academic / vocational qualification
  • Previous experience that provides the knowledge, skills, and abilities to perform the job (comparable to 2+ years). In some cases, an equivalency, consisting of a combination of appropriate education, training and/or directly related experience, will be considered sufficient for an individual to meet the requirements of the role.
  • Execute new technology/innovation evaluation for purification process
  • Strong biological scientific understanding
  • Experience with chromatography and filtration for biologics purification
  • Laboratory hands on skills
  • Ability to work in an upright and /or stationary position for 6-8 hours per day.
  • Repetitive hand movement of both hands with the ability to make fast, simple, repeated movements of the fingers, hands, and wrists to operate lab equipment.
  • Occasional mobility needed.
  • Occasional crouching, stooping, with frequent bending and twisting of upper body and neck.
  • Light to moderate lifting and carrying (or otherwise moves) objects including luggage and laptop computer with a maximum lift of 15-20 lbs.
  • Ability to access and use a variety of computer software developed both in-house and off-the-shelf.
  • Ability to communicate information and ideas so others will understand; with the ability to listen to and understand information and ideas presented through spoken words and sentences.
  • Frequently interacts with others to obtain or relate information to diverse groups.
  • Works independently with little guidance or reliance on oral or written instructions and plans work schedules to meet goals.
  • Requires multiple periods of intense concentration.
  • Performs a wide range of variable tasks as dictated by variable demands and changing conditions with little predictability as to the occurrence.
  • Ability to perform under stress.
  • Ability to multi-task.
  • Regular and consistent attendance.

Nice To Haves

  • Experience with bioanalytical assays and methods preferred
  • Internship or corporate experience

Responsibilities

  • Execute high through put scale down robotic purification as part of early and late stage process development, viral clearance, process characterization, and continuous process improvement studies.
  • Perform basic data acquisition and analysis, and documentation in electric lab notebooks.
  • Will develop economical, robust steps for recovering the target protein from bioreactor harvests using chromatography, filtration, and other separation techniques; developing downstream purification processes to be transferred to manufacturing; and perform laboratory scale process characterization studies.
  • Perform various bioanalytical assays, including HPLC, ELISAs and SDS-PAGE, to aid in rapid process development.
  • The candidate must possess strong written, oral, and collaborative skills in order to effectively communicate experimental procedures and results.
  • As appropriate, the candidate may supply technical support for pilot and/or GMP manufacturing of clinical materials.

Benefits

  • A choice of national medical and dental plans, and a national vision plan, including health incentive programs
  • Employee assistance and family support programs, including commuter benefits and tuition reimbursement
  • At least 120 hours paid time off (PTO), 10 paid holidays annually, paid parental leave (3 weeks for bonding and 8 weeks for caregiver leave), accident and life insurance, and short- and long-term disability in accordance with company policy
  • Retirement and savings programs, such as our competitive 401(k) U.S. retirement savings plan
  • Employees’ Stock Purchase Plan (ESPP) offers eligible colleagues the opportunity to purchase company stock at a discount
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