Formulation Scientist

GenScript/ProBio•Redmond, WA

2d•$80,000 - $120,000

About The Position

GenScript Biotech Corporation (Stock Code: 1548.HK) is a global biotechnology group. Founded in 2002, GenScript has an established global presence across North America, Europe, the Greater China, and Asia Pacific. GenScript's businesses encompass four major categories based on its leading gene synthesis technology, including operation as a Life Science CRO, enzyme and synthetic biology products, biologics development and manufacturing, and cell therapy. GenScript is committed to striving towards its vision of being the most reliable biotech company in the world to make humans and nature healthier through biotechnology. GenScript is looking for a highly motivated and scientifically rigorous Nanoparticle Formulation Scientist to join our RNA team. This position will focus on developing novel lipid nanoparticle formulations for RNA delivery.

Requirements

Master or PhD's degree in pharmaceutical science, chemistry, biochemistry, chemical engineering or related field, Master is preferred
Strong knowledge of lipid and polymeric nanoparticle delivery technologies
>4 years of relevant experience in nucleic acid delivery with hands-on experience in lipid nanoparticle formulation and characterization
Extensive experience with production and analytical characterization of nanoparticles
Proficiency in all molecular biology techniques for mRNA and protein expression (RT-PCR, ELISA, Western blot, Flow-cytometry, etc) and RNA-related analytics (ribogreen, gel electrophoresis, capillary electrophoresis, etc).
Works collaboratively with team members to support each other
Excellent communication and problem-solving skills
A sense of humility and an eagerness to continue to learn and contribute to a supportive team

Responsibilities

Develop new lipid nanoparticle formulations (lipid or other polymers) platform for mRNA, DNA, RNA, peptide delivery, to achieve targeted delivery for different disease needs, like neuronal, brain, muscle, bone marrow cell, etc.
Develop method for characterizing and evaluating physical characteristics for antibody decorated LNPs.
Process development for high throughput LNP preparation and downstream process to improve production efficiency.
Produce formulations for related RNA projects, supporting functional assays for in vitro evaluation.
Maintain relationships with customers, participate in scientific meetings or customer meetings.
Write study protocols, technical reports, and SOPs to support mRNA product development projects.
Interact with IP counsel to assist with patent prosecution.
Monitors supply inventory and identifies any products required.
Maintains work area, equipment, department and all storage areas in a clean, neat and orderly manner.
Perform other duties as needed.