Facilities Maintenance Supervisor

AstraZenecaLos Angeles, CA
Onsite

About The Position

The Facilities Maintenance Supervisor leads maintenance operations to ensure the safe, compliant, and highly reliable performance of critical manufacturing and facility systems supporting cell therapy production in Tarzana, CA. In a Cell Therapy environment, where products are often patient-specific and time-sensitive, this role is critical to maintaining uninterrupted operations, cleanroom conditions, and strict chain-of-identity and chain-of-custody controls Tarzana, CA. The role integrates reliability engineering principles with daily maintenance execution, focusing on eliminating repeat failures, reducing unplanned downtime, and improving asset lifecycle performance in a highly regulated environment governed by FDA expectations and advanced therapies guidelines. Success in this role requires the ability to: • Lead teams in a fast paced, patient-centric manufacturing environment • Balance speed, compliance, and precision • Anticipate and mitigate risks to critical, often irreplaceable batches • Drive transition from reactive to predictive maintenance strategies • Collaborate multi-functionally with Manufacturing, Quality, and Engineering to support 7 days cell therapy operations Ultimately, the Maintenance Supervisor plays a direct role in ensuring that life-saving therapies reach patients safely, reliably, and on time, by maintaining the integrity and performance of the systems that produce them.

Requirements

  • High school diploma/GED required.
  • 8+ years in industrial facilities maintenance/leadership experience
  • 4+ years of leadership experience in a pharmaceutical, biotech, or GMP regulated environment (medical device/food service may be acceptable.)

Nice To Haves

  • Technical diploma/apprenticeship in HVAC or Boiler maintenance.
  • Bachelor’s degree in Mechanical engineering or Facilities Management is a plus.

Responsibilities

  • Leadership & Team Management: Manage and mentor maintenance technicians; set clear expectations for safety, quality, and performance; lead daily tier meetings and shift handovers; build a culture of ownership, urgency, and continuous improvement; collaborate with Engineering, Quality, and Operations.
  • Maintenance Execution & Compliance: Ensure all activities meet GMP, FDA, and site standards; review and approve complete, accurate work orders; enforce CMMS usage (e.g., SAP); lead aspects of preventive and corrective maintenance and calibrations; maintain inspection readiness and support audits.
  • Reliability & Asset Management: Implement reliability‑centered maintenance; investigate failures using RCA and FMEA; improve MTBF and MTTR; identify and resolve “bad actor” equipment; partner on upgrades and lifecycle management.
  • Planning & Scheduling: Work with the Maintenance Planner to prioritize and schedule work; secure parts, tools, and permits in advance; validate and refine job plans; increase labor efficiency and minimize reactive work.
  • Safety, Health, and Environment (SHE): Enforce LOTO, confined space, and permit systems; conduct safety observations, audits, and incident investigations; lead by example to sustain a zero‑incident culture.
  • Continuous Improvement: Remove waste from maintenance processes; increase schedule compliance, PM efficiency, and spare‑parts management performance; lead or participate in Kaizen and Lean initiatives.

Benefits

  • A qualified retirement program [401(k) plan]
  • Paid vacation, holidays, and paid leaves
  • Health benefits including medical, prescription drug, dental, and vision coverage in accordance with the terms and conditions of the applicable plans. Additional details of participation in these benefit plans will be provided if an employee receives an offer of employment.

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What This Job Offers

Job Type

Full-time

Career Level

Manager

Education Level

High school or GED

Number of Employees

5,001-10,000 employees

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