Executive Director, Oncology Head, Translational Development

Bristol Myers Squibb • Princeton, NJ

1d • Hybrid

About The Position

Working with Us Challenging. Meaningful. Life-changing. Those aren’t words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You’ll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams. Take your career farther than you thought possible. Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more: careers.bms.com/working-with-us. Context Bristol Myers Squibb is an integrated global biopharmaceutical company engaged primarily in the discovery, development and commercialization of novel therapies for the treatment of cancer, cardiovascular and inflammatory diseases. BMS R&D is at a critical and exciting phase of development. As it expands and integrates its portfolio, there is an opportunity for a dynamic and resourceful individual to lead our oncology efforts in Translational Development at our sites in New Jersey or Cambridge, MA. Translational Development at BMS Translational Development is part of the Global Research organization in BMS and leads late stage translational research and development activities for the late-stage portfolio. Translational Development supports all therapeutic areas (heme/onc, immunology, cardiovascular, and neuroscience). This group integrates scientific, strategic and business insights to lead the development of translational strategies at the franchise level and implements them in project teams to maximize the potential of BMS drugs for patients. Summary Reporting to the VP, Translational Development, the incumbent will be part of the translational team based in either Cambridge, MA or Summit, NJ and will help develop translational disease and asset strategies in solid tumor disease areas for assigned programs for approval or life-cycle management of the BMS pipeline (excluding CART). Key responsibility of this role is to lead the breast disease area strategy and a cross functional team of asset and disease scientists with deep disease, drug development and business knowledge working closely with discovery and early development teams, late clinical development as well as the broader oncology TD team

Requirements

• In-depth understanding of Oncology, especially Breast Cancer or Prostate, clinical landscape, evolving therapy, competitive landscape
• Strong understanding of clinical, translational and mechanistic data with therapeutics development
• Strong background in genetics, cancer biology and/or immunology
• Experience in deploying biomarkers for trial design including MRD guided designs, endpoints
• Experience in reverse translation with discovery experience a plus
• Experience in disease strategy development working cross-functionally
• Understanding of late-stage drug and translational development process
• Proven track record of drug submissions, approvals, regulatory interactions and label negotiations
• Proven ability to work with global disease teams to develop strategies to support life cycle management efforts tailored to regional markets (i.e., US, EU, CAN)
• Strong verbal and written communication skills with experience in developing written documents such as primary manuscripts/publications/reviews, disease strategies, mechanism slides, regulatory submissions, strategic communications, literature/market/pt segment analyses
• Proven success in spearheading collaborative scientific initiatives internally and with academic partners
• MD/PhD in Oncology or related field with minimum 15 years industry setting
• Track record in large and/or small companies, leading innovative efforts to deploy translational strategies
• Excellent communication, managerial and scientific qualities
• Ability to interact effectively across boundaries using influencing and relationship building skills.
• Competence in analysis and solving of problems, and the ability to prioritize and make tradeoffs to achieve goals.
• A problem solver who creatively and knowledgably transcends departmental function to act as a resource to entire research effort and senior managers in development.
• Identifies issues early and proposes innovative solutions.
• Communicates within the larger organization and external community.
• Provides expert guidance to multi-disciplinary teams and senior management.
• A leader whose scope of influence stretches across BMS.
• A leader who influences external scientific community.
• Expertise in the integration of preclinical research and clinical drug development
• Management experience with the ability to set priorities, direct projects and implement complex strategies and work on cross-functional teams
• Highly effective teamwork and interpersonal skills and the ability to work across numerous scientific disciplines

Responsibilities

• Leads the development of disease and asset specific translational annual goals and objectives for Translational Development (for internal /external, translational collaboration, compound specific plans, open research questions etc)
• Builds disease area specific long term translational strategy and implementation across portfolio
• Assists in developing and maintaining group budget and workforce plan
• Represents Translational Development in cross-functional Strategy Teams and business development teams
• Interfaces with commercial including early commercialization group and Medical Affairs to provide scientific support for cross-functional TD goals
• Accountable for regulatory submissions, regulatory interactions, health authority interactions for the team
• Communicates regularly and prepares and makes presentations for leadership and externally as required
• Collaborates with TD Lab Head in setting translational lab research objectives
• Collaborates with informatics, data science and biostats heads in setting translational research objectives
• Collaborates with Diagnostic Head to coordinate diagnostic needs and patient selection hypotheses
• Collaborates with early clinical development and discovery teams to leverage TD data and insights for early programs
• Evaluating, in conjunction with BD and established teams, the potential for in-licensing opportunities that may include potential therapeutics, emerging technologies, processes or capabilities that will enhance our Drug Discovery and Early Development efforts
• Liaises with key BMS research discovery and early translational groups to help formulate and execute on new hypotheses driving new clinical biomarker assays for unmet need segments, disease strategy for new targets and development candidates and ensure seamless transition of programs after proof-of-concept
• Serves as translational representative on BMS cross functional Disease Strategy Team and interfaces with commercial, clinical, Project leadership and regulatory teams to define patient segments of unmet need based on rapidly evolving clinical programs and commercial landscape
• Leads small and large strategic collaborations with academia and industry partners to identify biobanks, clinical trials and existing databases to collate multi-parameter genomic and clinical datasets to mine for novel biomarkers of unmet need patients in conjunction with computational biologists, data scientists and statisticians
• Serves as a conduit to external thought leaders and scientific consultants

Benefits

• Health Coverage: Medical, pharmacy, dental, and vision care.
• Wellbeing Support: Programs such as BMS Well-Being Account, BMS Living Life Better, and Employee Assistance Programs (EAP).
• Financial Well-being and Protection: 401(k) plan, short- and long-term disability, life insurance, accident insurance, supplemental health insurance, business travel protection, personal liability protection, identity theft benefit, legal support, and survivor support.
• Work-life benefits include: Paid Time Off US Exempt Employees: flexible time off (unlimited, with manager approval, 11 paid national holidays (not applicable to employees in Phoenix, AZ, Puerto Rico or Rayzebio employees) Phoenix, AZ, Puerto Rico and Rayzebio Exempt, Non-Exempt, Hourly Employees: 160 hours annual paid vacation for new hires with manager approval, 11 national holidays, and 3 optional holidays Based on eligibility, additional time off for employees may include unlimited paid sick time, up to 2 paid volunteer days per year, summer hours flexibility, leaves of absence for medical, personal, parental, caregiver, bereavement, and military needs and an annual Global Shutdown between Christmas and New Years Day. All global employees full and part-time who are actively employed at and paid directly by BMS at the end of the calendar year are eligible to take advantage of the Global Shutdown.
• Eligibility Disclosure: The summer hours program is for United States (U.S.) office-based employees due to the unique nature of their work. Summer hours are generally not available for field sales and manufacturing operations and may also be limited for the capability centers. Employees in remote-by-design or lab-based roles may be eligible for summer hours, depending on the nature of their work, and should discuss eligibility with their manager. Employees covered under a collective bargaining agreement should consult that document to determine if they are eligible. Contractors, leased workers and other service providers are not eligible to participate in the program.

What This Job Offers

• Job Type: Full-time
• Career Level: Executive
• Education Level: Ph.D. or professional degree