Executive Director Global Product Leader, Oncology R&D

AstraZeneca • Waltham, MA

279d

About The Position

Join us at AstraZeneca as an Executive Director Global Product Lead (GPL) in Oncology R&D. This role offers the opportunity to lead and be accountable for multiple global cross-functional early global product teams across diverse biological mechanisms. As the 'CEO' of the asset, you will have the chance to make a big impact and be part of the team that aims to eliminate cancer as a cause of death. The Executive Director Global Product Lead (GPL) will have overall leadership and accountability of multiple global cross functional early global product teams across diverse biological mechanisms from candidate selection through Phase III investment decision across 3 of the major platforms (IO, ADC, Cell Therapy). This individual will be accountable for the strategic leadership and execution for the product candidates (essentially the ‘CEO' of the asset). You will have oncology clinical drug development experience, demonstrated leadership, and be able to critically evaluate the science, clinical data and competitive landscape that underlies these programs. You will be able to effectively communicate across a broad range of audiences and have an ability to clearly articulate project specific strategies as it relates to the overall oncology strategy.

Requirements

• Graduate degree such as a PhD, PharmD or an MD/PhD is required.
• 10+ years experience leading oncology drug development.
• Demonstrated success in developing oncology agents.
• Industry experience in drug development including experience in early phase non-clinical and/or clinical drug development and regulatory knowledge.
• Strong knowledge and understanding of the Oncology therapeutic area with experience in diverse biological mechanisms.
• Broad understanding of the evolving clinical landscape in oncology.
• Demonstrated experience leading and motivating teams in a highly matrixed environment.
• Proven record of cultivating and managing internal and external cross-functional collaborations.
• Demonstrated success in influencing colleagues and senior leaders in various departments.
• Must demonstrate high integrity.

Nice To Haves

• Experience in the development of biologics is highly desirable.
• ADC/ IO/ Radio Conjugates (T cell engagers, immune redirecting agents, cell therapy, etc) development experience is highly desirable.
• Due diligence experience as GPLs often are required to participate in business development.

Responsibilities

• Leads global product teams from preclinical candidate selection through proof of concept leading to Phase III Investment decisions.
• Single point of accountability for the strategy, budget, timeline and execution of a portfolio of pre-clinical and clinical stage therapeutic candidates.
• Create integrated product development plans which are aligned with business objectives and are differentiated from competitor products.
• Leads and communicates the project development strategy at governance meetings to secure funding and endorsement of the strategy.
• Leads the global project team to effectively manage/mitigate/communicate risk.
• Responsible for monitoring emerging data and pivot when deemed necessary.
• Responsible for maintaining a high degree of team effectiveness through collaboration, influence, and, as necessary, coaching and mentoring of cross-functional team members.
• Maintains relationships with external investigators to ensure projects are consistent with evolving clinical.

Benefits

• Flexible working arrangements with a minimum of three days per week in the office.
• Commitment to lifelong learning, growth and development for all.
• Inclusive and equitable environment where people belong.

What This Job Offers

• Job Type: Full-time
• Career Level: Executive
• Industry: Chemical Manufacturing
• Education Level: Ph.D. or professional degree