Executive Director, DMPK

Frontage Lab • Exton, PA

44d • Onsite

About The Position

The successful candidate will lead the in vitro ADME and pharmacokinetic functions of the DMPK department at the Exton, PA site. The position involves overseeing a group of approximately 20 scientists performing studies to evaluate the pharmacokinetics, drug metabolism and drug-drug interaction potential of development and discovery-stage drugs.

The successful candidate will be responsible for setting performance and financial goals for the business unit and ensuring the required resources/personnel are in place to achieve the goals.

Requirements

• PhD in chemistry, biology, or related area
• More than 10 years of related experience in the biotech, pharma or preclinical CRO industry
• Solid knowledge of in vitro DMPK, drug transporters, enzyme kinetics and pharmacokinetics
• Familiarity with bioanalysis using LC/MS/MS
• Experience with drug discovery and development and the toxicology, drug metabolism, and pharmacokinetics data required at various stages of the drug discovery and development process
• Good track record in leading small to large DMPK groups

Responsibilities

• Keep abreast of new scientific developments and regulatory requirements and ensure the work within the group is performed accordingly
• Have a general strategy of soliciting business, meet customers and provide scientific input so that the right studies are performed to address the scientific and/or regulatory question at hand
• Design studies as needed and include in study proposals /protocols
• Prepare study proposals at the request of customers
• Provide guidance in the preparation of study protocols for in vitro and in vivo studies
• Help with the interpretation of data and conclusions/summaries for completed studies
• Ensure that all studies are conducted efficiently and in a timely manner while maintaining highest quality of data
• Ensure that the scientists follow Frontage SOPs, DMPK guidelines, and study protocols while conducting studies
• Other duties as assigned

What This Job Offers

• Job Type: Full-time
• Career Level: Executive
• Industry: Professional, Scientific, and Technical Services
• Education Level: Ph.D. or professional degree
• Number of Employees: 501-1,000 employees