Executive Director, Biostatistics

Bristol Myers Squibb•San Diego, CA

19h

About The Position

Working at Bristol Myers Squibb offers challenging, meaningful, and life-changing opportunities for growth and transformation, supported by competitive benefits and programs that promote balance and flexibility. RayzeBio, a part of Bristol Myers Squibb, is actively seeking an experienced and visionary Executive Director of Biostatistics. This pivotal role involves leading theranostic (imaging and therapeutic) development within the Biometrics department. The successful candidate will bring deep expertise in biostatistical methodologies, provide strategic vision, offer regulatory leadership, and exert cross-functional influence throughout the entire drug development process. Key responsibilities include mentoring and developing the internal statistics team, enhancing statistical processes and Standard Operating Procedures (SOPs), and ensuring RayzeBio maintains submission and inspection readiness as its pipeline expands. Furthermore, this position holds expanded organizational accountability to champion the thoughtful adoption and integration of AI and machine learning innovations across the Biometrics function, thereby enabling more efficient, rigorous, and forward-looking clinical development at RayzeBio.

Requirements

Advanced degree in Statistics or Biostatistics
15+ years of biostatistics experience in pharmaceutical/biotech industry.
Solid understanding of GCP, ICH guidelines, and regulatory requirements.
Prior oncology experience
Proven track record of leadership, mentoring, and team development.
Ability to balance strategic leadership with hands-on execution of statistical analyses and deliverables.
Excellent interpersonal and communication skills, with the ability to influence cross-functional stakeholders.
Able to function in a highly regulated environment and to adhere to all RayzeBio guidelines and standard operating procedures (SOPs).

Nice To Haves

PhD in Statistics or Biostatistics.
Radiopharmaceutical experience.

Responsibilities

Lead end-to-end statistical strategy for clinical programs from early-phase through NDA/MAA submissions and product launch.
Provide statistical leadership for regulatory interactions, including FDA/EMA meetings, Advisory Committees, inspection readiness, and submission deliverables.
Design and implement innovative trial methodologies to accelerate clinical development while ensuring statistical rigor and regulatory alignment.
Collaborate with cross-functional teams to drive development decisions and integrate statistical perspectives into program strategies.
Oversee biostatistics deliverables, including protocol development, SAPs, TFLs, and CSRs, ensuring accuracy, quality, and timely completion.
Partner with internal programming and data management teams to support regulatory requests, publications, safety updates, and exploratory analyses.
Participate in and lead internal sponsor reviews of ongoing trial data, providing clear statistical insights for decision-making.
Oversee resource allocation and budget planning for biostatistics activities across assigned programs.
Build and mentor a high-performing project team, provide coaching and career development to direct reports.
Develop and establish SOPs and best practices within biostatistics and programming.
Serve as the Biometrics lead for AI-related initiatives, partnering with internal stakeholders and external vendors to explore and pilot AI solutions that support quality control and operational efficiency.
Streamline and standardize Biometrics processes to enable consistent and compliant implementation of approved AI tools.
Willing to travel approximately 10% of the time.
Evening and weekend work will be involved.
Utilize AI as a lever for scientific, operational, and commercial advantage.

Benefits

Medical care
Pharmacy care
Dental care
Vision care
BMS Well-Being Account
BMS Living Life Better
Employee Assistance Programs (EAP)
401(k) plan
Short- and long-term disability
Life insurance
Accident insurance
Supplemental health insurance
Business travel protection
Personal liability protection
Identity theft benefit
Legal support
Survivor support
Flexible time off (unlimited, with manager approval, for US Exempt Employees)
11 paid national holidays (not applicable to employees in Phoenix, AZ, Puerto Rico or Rayzebio employees)
160 hours annual paid vacation for new hires with manager approval (for Phoenix, AZ, Puerto Rico and Rayzebio Exempt, Non-Exempt, Hourly Employees)
11 national holidays (for Phoenix, AZ, Puerto Rico and Rayzebio Exempt, Non-Exempt, Hourly Employees)
3 optional holidays (for Phoenix, AZ, Puerto Rico and Rayzebio Exempt, Non-Exempt, Hourly Employees)
Unlimited paid sick time (based on eligibility)
Up to 2 paid volunteer days per year (based on eligibility)
Summer hours flexibility (based on eligibility)
Leaves of absence for medical, personal, parental, caregiver, bereavement, and military needs
Annual Global Shutdown between Christmas and New Years Day (for all global employees full and part-time who are actively employed at and paid directly by BMS at the end of the calendar year)