Engineering Co-op, Downstream Process Development

Myonexus Therapeutics • Burlington, MA

275d • $22 - $34

About The Position

The co-op in gene therapy downstream process development will give insight into the manufacturing process for complex viral vectors along with hands-on production experience using bioprocessing techniques - including depth filtration, tangential flow filtration, and liquid chromatography. The co-op student will not only have the opportunity to interact with the downstream team, but also the upstream, analytical development, and formulation teams to learn how drug products are developed safely, cost-effectively, and efficiently from lab scale (≤10L) to commercial scale (>1000L). In addition, co-op students will be exposed to leading-edge development approaches and technologies used to overcome major challenges in the bioprocessing sector, such as design of experiments, process intensification, and high-throughput automation. Timing permitting, the co-op will also experience what goes into tech transfer at the early-stage development site. The highly collaborative environment of Sarepta Therapeutics will expose the co-op to the nature of the job of multiple teams, departments, and leadership in getting therapeutic molecules from research to the clinic.

Requirements

• Undergraduate (junior or senior) or graduate student majoring in a science-oriented field, preferably (but not limited to) chemical engineering, bioengineering, biomedical engineering.
• One year of laboratory research experience or equivalent is preferred.
• Experience with protein purification is preferred.
• Proficiency in Microsoft Office (Word, Excel, PowerPoint) is required.

Nice To Haves

• Experience with statistical software such as JMP or SIMCA is a plus.

Responsibilities

• Assist downstream scientists in the design, preparation, and execution of process development experiments.
• Work independently on a research project aimed at optimizing a select unit operation within the downstream process for AAV manufacturing.
• Participate in weekly process development meetings.
• Refinement of laboratory skills via introduction to new experimental techniques, exposure to current challenges in bioprocess research, and perspectives on the practical aspects of drug development.

Benefits

• Competitive compensation and benefit package.

What This Job Offers

• Job Type: Full-time
• Career Level: Intern
• Education Level: Bachelor's degree