Spear Bio, founded in 2021, is a well-funded and rapidly growing biotech start-up headquartered in Woburn, Massachusetts. Our proprietary technology, Successive Proximity Extension Amplification Reaction (SPEAR), is a novel wash-free immunoassay platform, offering unprecedented sensitivity. We are dedicated to revolutionizing early disease diagnosis and monitoring by providing scalable, ultrasensitive solutions that deliver unparalleled accuracy in measuring low-abundant biomarkers, enabling clinicians and researchers to improve patient outcomes and advance global health. We are seeking a Systems Test Engineer to establish and execute systematic testing strategies across assay workflows and integrated engineering systems. This role requires a strong understanding of where immunoassays/nucleic acid assays and systems intersect, with the ability to design rigorous test frameworks, validate performance across biology and hardware/software interfaces, and identify root causes of failures. You will ensure that Spear Bio’s integrated platforms deliver reliable, reproducible, and high-quality results.