Downstream Associate

Sino Biological • Houston, TX

79d

About The Position

This is an entry-level position suitable for individuals seeking hands-on experience in protein purification and quality control in an industrial bioprocessing environment. The Associate will support the downstream team in executing purification workflows and conducting protein characterization assays to evaluate product quality.

Requirements

• Bachelor's degree in Biology, Biochemistry, Biotechnology, or a related field.
• 0-3 years of relevant laboratory experience, with basic understanding of protein purification and analytical methods.
• Familiarity with chromatographic systems such as FPLC or HPLC used for protein purification.
• Experience or exposure to protein QC analytical assays, such as SDS-PAGE, HPLC-SEC, and endotoxin testing and ELISA.
• Strong organizational and documentation skills, with attention to detail.
• Willingness to work a flexible schedule, including early/late weekday shifts and occasional weekend work depending on project needs.
• Good communication skills and a collaborative team mindset.
• Must be able to lift and move 25-50 lbs as needed.

Responsibilities

• Perform purification of recombinant proteins and antibodies from mammalian expression systems using chromatography methods and equipment (e.g., AKTA systems).
• Execute established downstream workflows to meet project specifications and client requirements.
• Conduct protein quality control testing, including SDS-PAGE, HPLC-SEC, endotoxin assays, UV-Vis concentration measurement, and other analytical assays.
• Support lead scientists in preparing and analyzing QC data and interpreting protein quality results as part of downstream bioprocessing, including purification and quality control.
• Maintain accurate batch records, lab notebooks, and QC documentation in compliance with internal standards and client requirements.
• Ensure compliance with laboratory safety protocols and PPE usage in accordance with federal, state, and local regulatory guidelines.
• Assist with calibration, maintenance, and basic troubleshooting of chromatography and analytical instruments.
• Collaborate with other teams within the Center to support smooth project coordination and delivery.

Benefits

• Competitive compensation package.
• Learn directly from industry professionals in a global biotech company.
• Career growth opportunities and mentorship.
• A welcoming, team-first workplace that celebrates diversity and collaboration.

What This Job Offers

• Career Level: Entry Level
• Industry: Chemical Manufacturing
• Education Level: Bachelor's degree
• Number of Employees: 251-500 employees