Distinguished Scientist, Multiomics Discovery – Therapeutics Discovery

Johnson & Johnson•Ambler, PA

3d•Onsite

About The Position

At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at https://www.jnj.com About Innovative Medicine Our expertise in Innovative Medicine is informed and inspired by patients, whose insights fuel our science-based advancements. Visionaries like you work on teams that save lives by developing the medicines of tomorrow. Join us in developing treatments, finding cures, and pioneering the path from lab to life while championing patients every step of the way. Learn more at https://www.jnj.com/innovative-medicine We are searching for the best talent for a Distinguished Scientist, Multiomics Discovery to be located in Spring House, PA or Cambridge, MA. Purpose: Discovery Technologies & Molecular Pharmacology (DTMP) has established over 20 high‑throughput, high‑dimensional Multiomics platforms that have generated more than 2.5B data points over the last five years. We are recruiting a Director‑level Distinguished Scientist — an individual contributor and matrix leader — to serve as subject matter expert for Multiomics across internal teams and external collaborators. This role will interpret high‑dimensional platform outputs, support data/metadata quality and provenance, prioritize cross‑platform experiments, and translate integrated evidence into actionable decisions for target ID/validation, modality selection, biomarker development, early safety signals, and patient stratification from target concept to NME. Structured without direct reports to preserve deep technical focus, the Distinguished Scientist will exert matrix influence across Therapeutic Area partners, translational teams, Therapeutic Discovery modality groups, IT, DSDH, ISD, and internal discovery teams to accelerate time‑to‑insight and improve ROI on platform investments. Critically, this individual will lead and shape external scientific partnerships, engage academic collaborators, consortia, CROs, and industry partners to drive Multiomics innovation, negotiate technical strategies and data sharing, and expand Multiomics capabilities while delivering measurable portfolio impact.

Requirements

Education: A PhD in Computational Biology, Biology, Bioinformatics or a related field is required.
10+ years of experience in computational technology development and drug discovery, with demonstrated expertise in applying computational biology to drive program progression is required.
Exceptional communication skills and experience working in cross-functional, matrixed environments is required.
Proven ability to manage strategic initiatives and lead high performing teams through matrix leadership is required.
Proficiency in programming languages such as R or Python is required.
Established track record using computational biology to address complex biology questions through evidence of publications and portfolio impact is required.
Willingness to travel domestically and internationally up to approximately 20% is required.

Nice To Haves

Familiarity with diverse modalities including biologics, small molecules, peptides, antibody drug conjugates, and targeted protein degraders is preferred.
Experience cultivating and developing relationships to identify and leverage opportunities to meet the evolving organizational needs is preferred.
Evidence of innovation and ability to keep up with the rapid pace of scientific advancement in computational biology, AIML, and Multiomics data integration is highly preferred.

Responsibilities

Innovative Multiomics Interrogation and Applications: Developing and implementing advanced platforms that integrate in vitro, in vivo, human, and molecular data to generate robust hypotheses and simulate biological processes.
Platform Integration & Tool Development: Leveraging innovative foundation models to enhance and streamline assay development, translational biology, and safety predictions. Lead the creation of tools that integrate biological insights across molecular, cellular, and organismal scales.
Data-Driven Discovery: Partnering with internal wet and dry lab collaborators within Multiomics discovery as well as external TA, DSDH, IT, and ISD partners, oversee efforts to generate and integrate diverse data streams to uncover critical insights that drive therapeutic breakthroughs.
Strategic Vision & Leadership: Defining and implementing a transformative roadmap in vitro / in vivo correlations to enable human translation through integrated Multiomics. Matrix leadership across scientific domains and functions.
Therapeutic Innovation & Collaboration: Championing novel approaches to therapeutic hypothesis generation and modality selection, partner with data science, translational, and discovery teams to accelerate the journey from discovery through development.

Benefits

Under current guidelines, this position is eligible for an annual performance bonus in accordance with the terms of the applicable plan. The annual performance bonus is a cash bonus intended to provide an incentive to achieve annual targeted results by rewarding for individual and the corporation’s performance over a calendar/performance year. Bonuses are awarded at the Company’s discretion on an individual basis.
Subject to the terms of their respective plans, employees and/or eligible dependents are eligible to participate in the following Company sponsored employee benefit programs: medical, dental, vision, life insurance, short- and long-term disability, business accident insurance, and group legal insurance.
Subject to the terms of their respective plans, employees are eligible to participate in the Company’s consolidated retirement plan (pension) and savings plan (401(k)).
This position is eligible to participate in the Company’s long-term incentive program.
Vacation –120 hours per calendar year
Sick time - 40 hours per calendar year; for employees who reside in the State of Washington –56 hours per calendar year
Holiday pay, including Floating Holidays –13 days per calendar year
Work, Personal and Family Time - up to 40 hours per calendar year
Parental Leave – 480 hours within one year of the birth/adoption/foster care of a child
Condolence Leave – 30 days for an immediate family member: 5 days for an extended family member
Caregiver Leave – 10 days
Volunteer Leave – 4 days
Military Spouse Time-Off – 80 hours