Director, Vector Biology

Legend Biotech • Philadelphia, PA

188d • $187,989 - $246,735 • Hybrid

About The Position

Legend Biotech is seeking Director, Vector Biology as part of the Exploratory Technology team based in Philadelphia, PA. We are seeking a highly experienced and strategic leader to join our Vector Biology team as Director. This role will oversee lentiviral vector (LVV) production and early process development, while managing a team of 10+ scientists and collaborating cross-functionally with internal and external stakeholders.

Requirements

• Ph.D. in Chemical Engineering, Virology, Molecular Biology, or a related field.
• Minimum of 5 years of industry experience in cell and gene therapy, with a focus on viral vector production.
• Proven leadership experience managing teams of 5 or more direct reports.
• Hands-on experience with LVV manufacturing using bioreactors and industrial-scale downstream processes.
• Strong understanding of CMC requirements for viral vectors.
• Deep knowledge and hands-on experience in viral vector technologies.
• Experience working with Contract Development and Manufacturing Organizations (CDMOs).
• Experience providing vector core services is a plus.

Responsibilities

• Lead and manage a team of 10+ direct reports within the Vector Biology group.
• Oversee lentiviral vector (LVV) production to support internal research initiatives.
• Provide conventional vector core services to internal stakeholders.
• Drive early-stage process development for LVV manufacturing, including upstream, downstream, and analytical workflows.
• Set strategic direction for LVV Chemistry, Manufacturing, and Controls (CMC).
• Represent the Vector Biology team in cross-functional collaborations with Discovery Research, Early Drug Development (EDD), and Technical Development teams.
• Lead internal and external technology transfers for LVV manufacturing.

Benefits

• Medical, dental, and vision insurance.
• 401(k)-retirement plan with company match that vests fully on day one.
• Equity and stock options available to employees in eligible roles.
• Eight weeks of paid parental leave after just three months of employment.
• Paid time off policy that includes 15 vacation days, 5 personal days, 5 sick days, 11 U.S. national holidays, and 3 floating holidays.
• Flexible spending and health savings accounts.
• Life and AD&D insurance.
• Short- and long-term disability coverage.
• Legal assistance.
• Supplemental plans such as pet, critical illness, accident, and hospital indemnity insurance.
• Commuter benefits.
• Family planning and care resources.
• Well-being initiatives.
• Peer-to-peer recognition programs.

What This Job Offers

• Job Type: Full-time
• Career Level: Senior
• Industry: Chemical Manufacturing
• Education Level: Ph.D. or professional degree
• Number of Employees: 1,001-5,000 employees