Director/Sr. Director, Business Development & Operations

BridgeBio Pharma-posted 5 months ago

$220,000 - $295,000/Yr

Full-time • Senior

San Francisco, CA

501-1,000 employees

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Calcilytix Therapeutics, an affiliate within BridgeBio Pharma, is developing encaleret, a negative allosteric modulator of the calcium-sensing receptor (CaSR) for the treatment of Autosomal Dominant Hypocalcemia Type 1 (ADH1), a genetic cause of hypoparathyroidism. Encaleret is currently being evaluated in a Phase 3 clinical study and has received Orphan Drug Designation from the US FDA, EMA, and PMDA as well as Fast Track Designation from the US FDA. Results from the Phase 2b clinical study of encaleret in patients in ADH1 were published in the New England Journal of Medicine.

Shape and communicate the company’s strategic direction through well-structured presentations that guide prioritization and resource allocation
Lead strategic analyses for program evaluation, including discounted cash flow modeling, and secondary research
Prepare a strategy to guide the successful US commercialization of encaleret
Develop and deliver executive-level PowerPoint presentations that effectively communicate strategic insights, corporate initiatives, and market analyses
Create high-quality visual materials for leadership offsites, Board of Directors meetings, investor discussions & communications, and internal alignment efforts
Ensure presentations are tailored to the audience, synthesizing technical and business content into clear, concise, and actionable messaging
Present and discuss findings of strategic analyses to a variety of audiences, including the Calcilytix team, leadership, and investors
Support corporate development and partnering strategy to ensure that Encaleret can be accessed by patients worldwide
Partner with Technical Operations and CMC teams to assess long-term supply chain capabilities and infrastructure needs
Develop strategic analyses related to contract manufacturers (CMOs), raw material sourcing, and distribution logistics
Contribute to make-vs-buy decisions, cost optimization, and supply chain resilience planning
Collaborate with R&D, Regulatory, Finance, Commercial, and Operations to ensure holistic strategy development
Collaborate with functional experts as a strategic partner to support the clinical and commercial success of Encaleret
Collaborate with the BridgeBio commercial team and oversee research in pricing and reimbursement
Lead or contribute to special initiatives involving product lifecycle planning, global expansion, or operational efficiency

A higher degree or equivalent, such as an M.B.A., M.D., or Ph.D., is preferred
2-5 years of professional experience in management consulting (life sciences preferred), post-Series A investing, investment banking, venture capital, equity research, and/or corporate role in a therapeutics company
Prior experience contributing to new product commercialization is a plus
Proven scientific acumen, communication skills, and an analytical mindset
A passion for helping patients
Proficiency in financial modeling, particularly DCF models
Tenure-appropriate understanding of the drug development life science and operating model
Tenure-appropriate understanding of the biotech landscape
Exceptional written communication and presentation skills

Market leading compensation
401K with 100% employer match on first 3% & 50% on the next 2%
Employee stock purchase program
Pre-tax commuter benefits
Referral program with $2,500 award for hired referrals
Comprehensive health care with 100% premiums covered - no cost to you and dependents
Mental health support via Spring Health (6 therapy sessions & 6 coaching sessions)
Hybrid work model - employees have the autonomy in where and how they do their work
Unlimited flexible paid time off - take the time that you need
Paid parental leave - 4 months for birthing parents & 2 months for non-birthing parents
Flex spending accounts & company-provided group term life & disability
Subsidized lunch via Forkable on days worked from our office
Career pathing through regular feedback, continuous education and professional development programs via LinkedIn Learning, LifeLabs, Spring Health & BetterUp Coaching
Celebration of strong performance with financial rewards, peer-to-peer recognition, and growth opportunities

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