Director, Program Management

Stoke Therapeutics • Bedford, MA

3d • $192,000 - $218,000 • Hybrid

About The Position

The role of the Director, Program Management is to partner with the development Program Leader to drive program planning and execution. The Director will be responsible for providing a combination of drug development, global commercialization, financial, and program management expertise to the Program Team (PT). This role, through partnership with the Program Leader, has significant responsibility for developing, driving, operationalizing, and executing program strategy. The candidate will have prior successful experience managing cross-functional teams in drug development. This individual will also be a strong influencer who can integrate multiple perspectives effectively, align stakeholders across functions and organization levels, problem-solve and achieve the program goals. This position will report into the SVP, Program Leadership and Management.

Requirements

• Minimum of 10 years total experience in pharmaceutical or biotechnology industry including participation on cross-functional drug development teams.
• BA/BS degree required; advanced medical, scientific or business degree strongly preferred.
• Strong understanding of the drug development lifecycle, including clinical development planning, regulatory milestones, and cross-functional dependencies.
• Demonstrated ability to drive complex programs forward in a matrixed environment, balancing strategic thinking with operational execution.
• Proven experience integrating cross-functional input into clear, actionable program plans and enabling teams to deliver against shared goals.
• Strong facilitation and communication skills, with the ability to guide discussions, clarify decisions, and align diverse stakeholders.
• Ability to anticipate program challenges and proactively develop mitigation strategies.
• Excellent organizational and analytical skills, with the ability to synthesize complex information into clear insights for leadership.
• Collaborative leadership style with strong relationship-building skills across functions and external partners.

Nice To Haves

• Experience supporting alliance or collaboration programs is a plus.

Responsibilities

• Develop and maintain the integrated program plans, translating development strategy into actionable timelines, milestones, decision points and cross-functional deliverables.
• Partner closely with the Program Leader to ensure the PT operates efficiently, enabling clear priorities, informed decision-making, and forward planning.
• Drive program execution by tracking progress against key milestones, identifying emerging risks or dependencies, and facilitating proactive mitigation strategies.
• Ensure cross-functional alignment across development subteams by coordinating planning, surfacing trade-offs, and clarifying accountabilities.
• Lead program-level risk identification and mitigation planning, maintaining visibility of key program risks and ensuring they are actively managed by the appropriate teams.
• Prepare program materials and insights for governance discussions, ensuring leadership has clear, concise information to support strategic decisions.
• Facilitate effective program team meetings and decision processes, ensuring discussions focus on critical issues, decisions, and execution priorities.
• Support resource and scenario planning with functional leaders to ensure program plans are achievable and appropriately resourced.
• Partner with Alliance Management to coordinate collaboration partner interactions, supporting operational alignment, joint governance preparation, and tracking of shared deliverables when applicable.
• Maintain clear communication of program status, key risks, and upcoming decisions to stakeholders across the organization.
• Enable effective operation of the PT by driving integration, alignment, and execution across functional subteams throughout the development lifecycle.

Benefits

• Our benefits package includes medical, dental and vision insurance; life, long- and short-term disability insurance; paid parental leave; a 401K plan with company match, unlimited vacation time, tuition assistance and participation in our Employee Stock Purchase Program (ESPP).

What This Job Offers

• Job Type: Full-time
• Career Level: Director