Director, Product Management - Early Cancer Detection (ECD) Software

Natera

13h

About The Position

Natera is at the forefront of personalized genetic testing, transforming the management of disease worldwide. We are at the cusp of a new inflection point with the development of our Early Cancer Detection (ECD) product that detects cancer earlier than ever before. We are seeking a seasoned and visionary Director of Product Management to lead the software product strategy and development for our ECD software portfolio. You will own the product roadmap for the full software stack, from sample ordering to report delivery, acting as the bridge between cutting-edge R&D, operations, and engineering. This role requires a leader who thrives in a "Zero-to-One" environment, possessing the strategic vision of a product leader combined with masterful execution. You will live the ethos of agile, user-centered development with high agency and urgency, driving the team to navigate ambiguity and deliver critical milestones in a highly regulated field.

Requirements

Experience: 10+ years of product management experience in healthcare IT, biotech, or software, with at least 5 years in a leadership role.
Zero-to-One Track Record: Proven experience building and launching "Zero-to-One" software products in a startup or internal incubator environment.
Regulated Industry Expertise: Deep experience in a highly regulated environment, with specific expertise in SaMD (Software as a Medical Device), FDA design controls, and HIPAA/GDPR compliance.
Project Management Prowess: Demonstrated ability to drive complex projects to completion, managing timelines, dependencies, and stakeholders effectively.
Technical Aptitude: Strong ability to understand technical complexities and communicate effectively with engineering and scientific teams.
Education: BS/MS in a relevant technical, scientific, or quantitative discipline (MBA or PhD is a plus).

Nice To Haves

Familiarity with NGS (Next-Generation Sequencing), liquid biopsy, or oncology diagnostics is highly desirable.

Responsibilities

Define the ECD Software Vision: Develop and execute the multi-year software product roadmap for the ECD business unit, balancing the need for rapid prototyping with long-term commercial stability and regulatory compliance.
Champion a culture of "high agency" and urgency, driving the team to make quick, data-driven decisions in ambiguous situations and deliver critical milestones in a fast-paced environment.
Serve as the product expert for the ECD software suite, translating complex scientific, clinical, and regulatory requirements into robust, scalable software product requirements.
Ensure the software roadmap aligns with broader business goals, R&D timelines, and commercial launch strategies.
Lead the "Zero-to-One" product development lifecycle for ECD software solutions, covering the full stack from sample receipt to report delivery.
Passionately advocate for the needs of internal users (lab scientists, accessioning teams) and external customers (clinicians, patients), ensuring software solves real problems.
Drive project execution with the rigor of a seasoned project manager, ensuring cross-functional teams (Product, Engineering, R&D, Lab Ops, Commercial Ops) stay on track to meet critical deadlines.
Expert in Agile methodologies and software development lifecycles. Own the product backlog and drive Agile ceremonies, ensuring clear requirements, acceptance criteria, and timely feature delivery.
Exceptional written and verbal communication skills, with the ability to simplify complex ideas for diverse audiences and influence stakeholders at all levels.
Ability to see the "big picture" and understand how software systems interact across the entire sample lifecycle.
Partner with Quality and Regulatory (RA/QA) teams to ensure all software products comply with FDA (PMA/510k), IEC 62304, ISO 13485, HIPAA, and GDPR standards.
Proactively identify and mitigate product and project risks, ensuring robust documentation and compliance without compromising development velocity.
Champion data integrity, traceability, and operational efficiency in all ECD software initiatives.
Recruit, mentor, and retain a world-class team of product managers.
Foster a product culture of accountability, user experience rigor, and cross-functional collaboration within the ECD unit.
Mentor and guide product managers and cross-functional team members, instilling best practices in product management and agile development.

Benefits

Annual performance incentive bonus
Long-term equity awards
Comprehensive health benefits (medical, dental, vision)
401(k) with company match
Generous paid time off and company holidays
Additional wellness and work-life benefits
Employee benefits include comprehensive medical, dental, vision, life and disability plans for eligible employees and their dependents.
Additionally, Natera employees and their immediate families receive free testing in addition to fertility care benefits.
Other benefits include pregnancy and baby bonding leave, 401k benefits, commuter benefits and much more.
We also offer a generous employee referral program!