Director, Product Management- Biopharma

Guardant HealthPalo Alto, CA
11dHybrid

About The Position

The Director, Product Management- Biopharma is a leadership position reporting to our Senior Director of Product Management. You would lead the strategy, development, and commercialization of Guardant’s biopharma-focused diagnostics portfolio, ensuring our products are clinically impactful, scientifically rigorous, and aligned with the needs of our biopharma partners. Viable candidates will have deep expertise in oncology diagnostics, and a passion for driving innovation at the intersection of medicine, product strategy, and biopharma collaboration. While not a requirement, this is an ideal opportunity for clinically-trained MDs, PhDs, or MD/PhDs to work at the forefront of oncology diagnostics.

Requirements

  • A Bachelor’s degree and 15 years of related experience or 10-12 years with a Master’s degree; 8 years with a PhD; or 5 years with a PharmD/MD
  • 8+ years of experience in product management, medical affairs, or biopharma strategy within oncology diagnostics or precision medicine
  • Proven success in launching and scaling diagnostic or healthcare products
  • Strong understanding of liquid biopsy, molecular diagnostics, and biomarker-driven oncology

Nice To Haves

  • Master’s and/or advanced scientific degree is highly preferred
  • Experience in companion diagnostics, biomarker development, or clinical trial integration
  • Familiarity with payer dynamics, evidence generation, and reimbursement strategies
  • Exceptional communication, analytical, and leadership skills with the ability to influence across scientific, clinical, and commercial domains

Responsibilities

  • Strategic Leadership & Portfolio Management
  • Define and execute a comprehensive product strategy aligned with Guardant’s biopharma business objectives and oncology roadmap
  • Lead cross-functional teams to design, develop, and deliver best-in-class assay and digital products for therapy selection and disease monitoring
  • Translate market insights and partner needs into actionable product plans, identifying unmet needs and prioritizing opportunities
  • Biopharma Engagement & Innovation
  • Serve as the primary product liaison to the biopharma business unit, ensuring alignment with biomarker-driven trials, companion diagnostics, and regulatory strategies
  • Drive co-development partnerships and data generation initiatives to support product innovation and reimbursement
  • Monitor emerging trends, technologies, and competitive activity to inform product differentiation and future roadmap
  • Clinical Integration & Commercialization
  • Ensure products integrate seamlessly into oncology workflows—physician, nurse, and patient—to maximize adoption and usability
  • Collaborate with Medical Affairs and Market Access to develop evidence strategies that demonstrate clinical utility and support payer engagement
  • Oversee launch planning, sales enablement, and field training to ensure commercial readiness
  • Cross-Functional Collaboration
  • Partner with R&D, Clinical Development, Regulatory, and Commercial teams to drive execution across the product lifecycle
  • Represent Guardant externally with oncologists, healthcare systems, payers, and biopharma stakeholders to refine value propositions and identify unmet needs
  • Contribute to publication planning, clinical conference presentations, and scientific communications
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