Director, Molecular Pathology, Translational Sciences, Translational Research.
About The Position
Revolution Medicines is a clinical-stage precision oncology company focused on developing novel targeted therapies to inhibit frontier targets in RAS-addicted cancers. The company’s R&D pipeline comprises RAS(ON) Inhibitors designed to suppress diverse oncogenic variants of RAS proteins, and RAS Companion Inhibitors for use in combination treatment strategies. As a new member of the Revolution Medicines team, you will join other outstanding Revolutionaries in a tireless commitment to patients with cancers harboring mutations in the RAS signaling pathway. The Opportunity: As a Director, Molecular Pathology, you will be a key member of a cross-functional Translational Sciences Team, reporting to the Senior Director and Head of Translational Sciences within Translational Research and will: Biomarker Strategy: Define and execute molecular and digital pathology-driven biomarker strategies. Integration of Advanced Modalities: Lead adoption of molecular pathology and spatial technologies (to support translational research and broader BDR needs. Digital & Computational Pathology: Drive implementation of whole-slide imaging, AI/ML-based image analysis, and integration of spatial biomarker analytics into decision-making. Data Interpretation & Reporting: Provide expert interpretation of pathology data, ensuring robust correlation with clinical outcomes and mechanistic insights. Cross-functional Leadership: Collaborate with Translational Medicine, Bioinformatics, and Clinical Development colleagues to implement candidate biomarkers into Translational Biomarker plans for RAS(ON) inhibitors in alignment with overarching clinical development strategies.
Requirements
- Scientific Expertise: Deep knowledge of spatial biology; ability to translate complex data into actionable insights.
- Execution Excellence: Bias for action; delivers high-quality analyses under tight timelines.
- Collaboration & Influence: Builds strong relationships across functions and with external partners; communicates clearly and persuasively.
- Innovation & Continuous Improvement: Identifies opportunities to enhance workflows and adopt emerging technologies.
- PhD/MD or equivalent in Cancer Biology, Translational Sciences, Pathology or related discipline.
- 10+ years in digital pathology/spatial biology within pharma, biotech, or CRO settings.
Nice To Haves
- Hands-on experience with spatial pathology workloads.
- Familiarity with AI/ML-assisted pathology workflows and spatial statistics.
- Proven ability to manage CRO relationships and deliver time-sensitive biomarker analyses.
Responsibilities
- Scientific Leadership & Execution: Perform and interpret multiplex spatial biomarker datasets to inform Translational hypotheses and clinical strategies. Establish QC standards for data acquisition and analysis.
- Cross-Functional Collaboration: Partner within Research and Clinical teams to integrate spatial biomarker findings into translational plans. Collaborate with Systems Biology and Information Sciences teams to enable visualization tools
- External Partnership Management: Serve as primary scientific liaison to CROs for spatial biomarker workflows; review deliverables, troubleshoot issues, and drive continuous improvement.
- Capability Building: Document best practices and SOPs for spatial biomarker workflows; recommend platform upgrades and pilot evaluations.
Stand Out From the Crowd
Upload your resume and get instant feedback on how well it matches this job.
What This Job Offers
Job Type
Full-time
Career Level
Director
Education Level
Ph.D. or professional degree
