Director Commercial FP&A

Praxis Precision Medicines, Inc.
6h$200,000 - $220,000Remote

About The Position

Praxis Medicines is seeking a Commercial FP&A leader to serve as a strategic finance partner to our Commercial organization as we prepare for launch and scale toward a multi-billion-dollar revenue organization. This role will support near-term launch readiness while also building the financial capabilities, discipline and insights required to operate at commercial scale over time. This role sits within Finance but works in close, real-time partnership with Commercial, CMC and other cross-functional teams. The successful candidate will be deeply embedded in ongoing commercial workstreams, enabling forward-looking decision-making through continuous engagement rather than periodic reporting.

Requirements

  • 12–15+ years of experience in FP&A or strategic finance, with strong commercial exposure
  • Biopharma experience required, including experience supporting a commercial-stage company
  • Advanced financial modeling and analytical skills
  • Proven ability to influence and partner with senior stakeholders across Finance, Commercial and CMC
  • Strong business judgment and executive communication skills
  • Comfortable operating in a fast-paced, evolving environment with ambiguity

Nice To Haves

  • Experience supporting product launch and operating in a scaled commercial environment preferred

Responsibilities

  • Act as the primary FP&A partner to Commercial leadership, supporting brand strategy, launch planning and revenue forecasting from pre-launch through scale.
  • Perform revenue modeling, scenario and sensitivity analyses and key commercial assumptions as the business grows to multi-billion-dollar revenue levels.
  • Partner closely with CMC and Supply Chain teams on inventory assumptions, demand planning and working capital considerations.
  • Collaborate cross-functionally on pricing, gross-to-net, market access and demand dynamics.
  • Lead Commercial and CMC input into budgets, ongoing forecasts and long-range plans.
  • Evaluate investment decisions through ROI analysis and financial modeling to support prioritization and resource allocation.
  • Develop executive-ready materials that clearly communicate risks, opportunities and trade-offs.
  • Continuously improves forecasting tools, processes and analytical rigor to support a scaling commercial organization.

Benefits

  • 99% of the premium paid for medical, dental and vision plans
  • company-paid life insurance, AD&D, disability benefits, and voluntary plans to personalize your coverage
  • dollar-for-dollar match up to 6% on eligible 401(k) contributions
  • long-term stock incentives and ESPP
  • discretionary quarterly bonus
  • extremely flexible wellness benefit
  • generous PTO
  • paid holidays and company-wide shutdowns
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