Director, Clinical Supply Chain - Comparators/External Collaborations

Revolution Medicines•Redwood City, CA

4d•Hybrid

About The Position

Revolution Medicines is a clinical-stage precision oncology company focused on developing novel targeted therapies to inhibit frontier targets in RAS-addicted cancers. The company’s R&D pipeline comprises RAS(ON) Inhibitors designed to suppress diverse oncogenic variants of RAS proteins, and RAS Companion Inhibitors for use in combination treatment strategies. As a new member of the Revolution Medicines team, you will join other outstanding Revolutionaries in a tireless commitment to patients with cancers harboring mutations in the RAS signaling pathway. The Opportunity: The Director, Clinical Supply Chain – Comparators and External Collaborations is a hands-on leadership role responsible for building scalable processes for comparator sourcing needs across the clinical portfolio, ensuring uninterrupted, compliant and cost-effective supply. The Director will also lead clinical supply activities related to external strategic partnerships and clinical collaborations. Develop and lead Comparator Sourcing governing structure and operating model for the Clinical Supply Chain group focusing on overall demand and supply planning across all programs. Collaborate with clinical supply program and study leads to identify comparator and external collaboration product needs. Formalize a sourcing/delivery plan as part of the Demand & Operations process (D&OP) and develop processes to communicate status to all internal and external stakeholders. Assess and mitigate supply risks, including but not limited to potential shortages, vendor capacity, regulatory requirements, financial targets. Partner with PDM Strategic Sourcing group to develop and maintain partnerships with comparator sourcing vendors, support sourcing agreement negotiations and plans for sourcing diversification to build high-performance, resilient global supply networks. Ensures all externally sourced products comply with applicable GxP and global trade regulations. Accountable for comparator sourcing financial budgets and budget adherence across the global development portfolio. Develop and maintain comparator products master profiles, lead processes to resolve any product related issues, including but not limited to temperature excursions, deviations, product complaints. Develop and maintain applicable Key Performance Indicators (KPI’s). Review and evaluate applicable supply agreements. Partner with Alliance Management and internal stakeholders to provide supply related requirements applicable to external collaboration agreements and associated clinical studies.

Requirements

10+ years of Clinical Supply Chain operations experience.
Experience with global oncology trials across all phases of development.
Strong knowledge of global pharmaceutical procurement and contract/supply agreement execution.
Strong at comparator planning and sourcing strategies.
Bachelor’s degree in supply chain, Business, Engineering or Life Sciences.
Strong knowledge and experience with end- to end supply chain and demand/supply planning.
Strong vendor management and contract oversight skills.
Strategic thinker with strong tactical execution.
Excellent cross-functional leadership skills with effective communication skills.

Nice To Haves

Master’s degree (MS, MBA).
CPIM/CSCP certifications a plus.
Proven leadership in working with matrixed teams.
Knowledge and experience with outsourced manufacturing operations and strategic sourcing.
Effective, open and transparent communication skills (verbal and written).
Strong analytical, communication and executive level reporting skills.
Capable of working on multiple projects/tasks and able to meet timelines.
Self-starter with a high-level of comfort with ambiguity and complexity and the ability to multi-task while consistently delivering quality results.
Team-oriented, progressive thinker who enjoys participating in an innovative and creative work environment.

Responsibilities

Building scalable processes for comparator sourcing needs across the clinical portfolio, ensuring uninterrupted, compliant and cost-effective supply.
Lead clinical supply activities related to external strategic partnerships and clinical collaborations.
Develop and lead Comparator Sourcing governing structure and operating model for the Clinical Supply Chain group focusing on overall demand and supply planning across all programs.
Collaborate with clinical supply program and study leads to identify comparator and external collaboration product needs.
Formalize a sourcing/delivery plan as part of the Demand & Operations process (D&OP) and develop processes to communicate status to all internal and external stakeholders.
Assess and mitigate supply risks, including but not limited to potential shortages, vendor capacity, regulatory requirements, financial targets.
Partner with PDM Strategic Sourcing group to develop and maintain partnerships with comparator sourcing vendors, support sourcing agreement negotiations and plans for sourcing diversification to build high-performance, resilient global supply networks.
Ensures all externally sourced products comply with applicable GxP and global trade regulations.
Accountable for comparator sourcing financial budgets and budget adherence across the global development portfolio.
Develop and maintain comparator products master profiles, lead processes to resolve any product related issues, including but not limited to temperature excursions, deviations, product complaints.
Develop and maintain applicable Key Performance Indicators (KPI’s).
Review and evaluate applicable supply agreements.
Partner with Alliance Management and internal stakeholders to provide supply related requirements applicable to external collaboration agreements and associated clinical studies.