Director, Clinical Development

Revolution Medicines • Redwood City, CA

1d • Hybrid

About The Position

Revolution Medicines is a late-stage clinical oncology company developing novel targeted therapies for patients with RAS-addicted cancers. The company’s R&D pipeline comprises RAS(ON) inhibitors designed to suppress diverse oncogenic variants of RAS proteins. The company’s RAS(ON) inhibitors daraxonrasib (RMC-6236), a RAS(ON) multi-selective inhibitor; elironrasib (RMC-6291), a RAS(ON) G12C-selective inhibitor; zoldonrasib (RMC-9805), a RAS(ON) G12D-selective inhibitor; and RMC-5127, a RAS(ON) G12V-selective inhibitor, are currently in clinical development. As a new member of the Revolution Medicines team, you will join other outstanding professionals in a tireless commitment to patients with cancers harboring mutations in the RAS signaling pathway. The Opportunity: The Director, Clinical Development will contribute to the scientific, clinical, and operational scope of assigned study protocols. This role will work with the cross-functional teams for the design, execution, and monitoring of clinical studies, as well as oversee data review, interpretation, and communication to both internal and external stakeholders. Oncology and/or late-stage experience is preferred.

Requirements

• A PhD, PharmD or equivalent is required.
• Minimum 8+ years of experience in the pharmaceutical or biotechnology industry as a clinical scientist or related role.
• Proven leadership in a collaborative team setting and driven by a desire to deploy innovative approaches and technologies in a high-energy environment.
• Detail-oriented with ability prioritize tasks and function independently as appropriate.
• Strong organizational skills and an ability to interpret, discuss, and report trial/program level data effectively and identify trends.
• Proficient with software tools (Microsoft Office), Electronic Data Capture, and other custom web-based software.
• Excellent written and verbal communication skills.

Nice To Haves

• Strong experience with clinical data review and data quality assurance.
• Knowledge and experience with clinical trial management and oversight.
• Understanding and experience in clinical trial protocol and regulatory document authoring.

Responsibilities

• Develop and execute clinical development strategies and the Clinical Development Plan (CDP) with a focus on early-phase development.
• Lead cross-functional teams with oversight from senior team members to conduct clinical studies, including study start up, execution and close out activities, data review/analysis, and preparation of study reports.
• Oversee the development of program-level documents, including but not limited to clinical protocols, investigator’s brochure, clinical study reports, abstracts and manuscripts, presentations, and various other internal and external documents and communications as needed.
• Conduct ongoing data reviews; prepare and present summaries to internal and external stakeholders.
• Ensure trial implementation according to the protocol and analyze information to assess issues relating to protocol conduct and/or individual subject safety.
• Interact with internal and external stakeholders (investigators, study sites, vendors, committees, etc.) in support of clinical trial objectives; responds to or triages questions for appropriate escalation.
• Conduct literature reviews as needed.

What This Job Offers

• Job Type: Full-time
• Career Level: Director
• Education Level: Ph.D. or professional degree
• Number of Employees: 251-500 employees