Director BioAnalytical Services LCMS

Eurofins•Lenexa, KS

13d

About The Position

The Director of Bioanalytical Services – LCMS is an exciting opportunity to put your mark on the design and build out of a fully functioning lab and operation in support of LCMS and Chromatographic assay development, validation and sample analysis. The role will provide scientific, strategic, and operational leadership across all LCMS-based bioanalytical services. This role requires deep expertise in method development and validation for both small molecules (e.g., NCEs, metabolites) and biologics (e.g., peptides, proteins, ADCs, oligonucleotides) in biological matrices. You’ll lead a team of experienced scientists and work closely with clients to ensure timely, compliant, and high-quality data delivery.

Requirements

Ph.D. in Analytical Chemistry, Biochemistry, Pharmaceutical Sciences, or related field; M.S. with extensive experience considered.
10+ years of progressive experience in a bioanalytical lab environment, with a strong focus on both small molecule and biologics LCMS and supporting automation.
Demonstrated leadership in a CRO, pharmaceutical, or biotech setting.
Hands-on expertise in quantitative LC-MS/MS for both small and large molecules.
Deep understanding of regulatory expectations for bioanalytical method validation (GLP/GCP and ICH-M10 requirements).
Excellent communication, project management, and client-facing skills.

Nice To Haves

LCMS-based analysis of biotherapeutics including intact protein quantitation, peptide mapping, and oligonucleotide quantitation.
Familiarity with hybrid LBA-LCMS workflows (e.g., immunocapture-LCMS).
Experience in supporting PK/PD, toxicokinetic, and immunogenicity studies.

Responsibilities

Design and build out of laboratory and capabilities for LC-MS/MS bioanalytical services.
Lead LCMS bioanalytical operations for both small molecule and large molecule (biologic) programs.
Direct method development, validation, and regulated sample analysis under GLP/GCP/CLIA.
Build and mentor a high-performing team of scientists and technical staff.
Oversee implementation of LCMS strategies for complex modalities such as peptides, ADCs, and oligonucleotides.
Ensure regulatory compliance with FDA, EMA, and ICH guidance.
Manage departmental resources, project timelines, and instrumentation (e.g., SCIEX, Thermo, Waters, Watson).
Act as scientific liaison in client meetings, regulatory audits, and cross-functional collaborations.
Support business development and marketing with technical input for proposals and feasibility assessments.