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At Clasp Therapeutics, we are revitalizing immuno-oncology's promise with next-generation T cell engagers (TCEs). Our novel TCE therapeutics enable a patient's T cells to identify and specifically destroy tumor cells with absolute precision. Our medicines' high level of precision and specificity essentially eliminate the likelihood of on-target off-tumor toxicities that have occurred with other TCEs. We have targeted our molecules to hard-to-treat tumors bearing common cancer driver mutations. Our specific platform structure targets mutated protein fragments, or peptides, that are displayed by specialized HLA and are designed to draw T cells into close contact with tumor cells. The resulting immune synapse is highly similar to a natural HLA molecule-T cell receptor interface with a high level of sensitivity, triggering T cells to destroy tumor cells. This approach enables a highly genetically selective paradigm where every patient has the opportunity to respond to treatment. Founded in 2020, we are focused on bringing the outstanding science from our world-class founders to patients. In 2023, Clasp closed a $150 million Series A financing round led by Catalio Capital Management, Third Rock Ventures, and Novo Holdings. Clasp has created a vibrant culture with people who are committed to our mission in both our Cambridge, MA, and Rockville, MD sites.