This role will lead and drive the Sales and Operations Planning (S&OP) process for Casgevy, a commercially launched product within Vertex’s Cell and Gene Therapy portfolio. This is a critical role within the Vertex Supply Chain, that includes the ability to perform complex modeling, utilizing assumptions, demand and capacity to meet both short- and long-term requirements. The Associate Director will be responsible for working with the commercial team to align assumptions and the demand plan, External Manufacturing to work with CDMO’s to align capacity assumptions, Finance, Materials, Quality Control and Regulatory that will culminate in the monthly S&OP process. This role will be responsible for establishing and communicating key assumptions, as well as scenario management which often requires modeling outside of the current system to understand capacity / demand alignment and financial impact. Additionally, the AD will oversee several Key Performance Indicators (KPI’s) that are managed within the S&OP process and identifying areas for improvement. The Associate Director will use the dynamic capacity model to recommend scheduling strategies, future capacity needs, and capacity utilization strategies based on unexpected events (i.e. patient withdrawals, suite downtime, etc.). The selected individual will build and lead the monthly S&OP meetings and play an integral role in the development and communication of Vertex’s Cell and Gene Therapy assets. As the Cell and Gene Therapy Supply Chain matures at Vertex, this role will be responsible for the implementation of a new planning tool that will systematize the planning process. This involves working cross-functionality with finance, external manufacturing and materials management to identify and document requirements, and working with the integration team to implement. The output of this implementation will be an integrated plan that takes demand and capacity to create an output that will be implemented across CDMO’s, materials suppliers, testing sites and for financial purposes.