Commercial Strategy & Portfolio Management Lead

Arcutis Biotherapeutics

About The Position

The Commercial Strategy & Portfolio Management Lead serves as a strategic advisor and operational partner to the Chief Commercial Officer, supporting the leadership, effectiveness, and execution of the Commercial organization. Reporting directly to the CCO, this role combines enterprise-level commercial strategy, investment and portfolio governance, and cross-functional execution to ensure alignment, focus, and disciplined delivery of commercial priorities. This position plays a central role in shaping how commercial strategy is developed, resourced, and executed. You will lead the planning, prioritization, and optimization of commercial investments while ensuring that budgets, vendor partnerships, and operating processes support brand strategy, launch priorities, and long-term growth objectives. As a trusted advisor to senior commercial leadership, you will provide strategic insights, scenario planning, and risk assessments, translating executive direction into actionable plans and measurable outcomes.

Requirements

Bachelor’s degree in Finance, Business, Marketing, or related field.
10+ years of experience in commercial operations, finance, marketing operations, or vendor/budget management, biopharma or healthcare experience strongly preferred.
Proven ability to manage complex budgets and financial planning processes with high accuracy and attention to detail
Experience developing and managing SOWs, POs, vendor contracts, and agency relationships
Strong analytical, organizational, and problem-solving skills with the ability to translate financial information into actionable insights
Excellent communication and interpersonal skills; comfortable influencing across teams and levels
Advanced proficiency in Excel and financial tracking tools; familiarity with SAP/Oracle/Workday or similar systems a plus
Demonstrated ability to work in a fast-paced, evolving environment while managing multiple priorities and deadlines
Travel up to 30%.

Nice To Haves

MBA or other related advanced degree preferred.

Responsibilities

Partner closely with the CCO to provide strategic analyses, recommendations, and decision support on commercial priorities
Translate leadership objectives into clear plans, milestones, and accountability across the Commercial organization
Prepare executive-level materials for leadership meetings, operating reviews, and enterprise or Board updates
Facilitate Commercial leadership team meetings and cross-functional forums to drive alignment, decision-making, and execution
Monitor progress against key initiatives, proactively identifying risks, gaps, and interdependencies and recommending mitigation strategies
Lead commercial investment planning, forecasting, and portfolio governance to ensure resources are aligned with strategic priorities and growth objectives
Partner with Commercial leaders to evaluate trade-offs, conduct scenario planning, and optimize resource allocation across brands and initiatives
Drive transparency and accountability through performance reporting, insights, and metrics tied to commercial outcomes and ROI
Support long-range planning, launch readiness, and future-state operating model evolution as the organization scales
Own end-to-end Commercial budget oversight, tracking, and reporting in close collaboration with Finance
Establish and manage a best-in-class agency and vendor management framework, including oversight of SOWs, POs, invoicing, contract routing, and spend governance
Partner with Procurement, Legal, and Finance to ensure compliance, efficiency, and scalability of vendor operations
Ensure disciplined governance of commercial spend while enabling agility and speed of execution
Act as a central point of coordination across Commercial, Finance, Market Access, Medical, Legal, and Procurement
Enable effective execution by driving clarity on priorities, decisions, and ownership across stakeholders
Identify opportunities to improve operational effectiveness, streamline processes, and maximize the impact of commercial investments