CoE Senior Manager - Pain

Vertex Pharmaceuticals • Boston, MA

8d • Remote

About The Position

Job Description Vertex is seeking to hire a Senior Manager, Data Enablement, Infrastructure and Reporting for Pain Therapeutic Area, within the U.S. Market Access (USMA) department, who will be a key contributor in the Data & Analytics (D&A) Center of Excellence (COE) team. The role requires strong data and analytics experience as well as deep subject matter expertise of value & access strategies, with an in-depth understanding of U.S. pricing and reimbursement dynamics. This individual will contribute to the generation of market access specific insights that impact patient access to Vertex inline brands and pipeline therapies by informing market access strategy, as well as contracting, payer accounts, trade, and distribution activities. The ideal candidate will have strong proficiency in 3rd party and internal market access data sources and analytic tools. This individual will join a team of Vertexians who are passionate about patients, focused on driving positive results, strategically adept, and willing to be involved in hands-on execution. This position will be part of the broader, US Market Access Data & Analytics Center of Excellence, and will matrix into the Engagement Lead for Pain Access & Insights. Support the development of insights to strengthen Vertex’s leadership in Pain Therapy Area and contribute to broader market access portfolio strategies by analyzing trends in the evolving market access landscape, to drive in-line brands and pipeline asset advancements in Pain therapy area. Execute analytical insights to inform US market access in-market growth activities within Pain, including evaluating in-market analogues for informing market access strategy, pricing & contracting, payer/PBM landscape, clinic/hospital economics, etc. Conduct Payer Access analytics to quantify and validate market access-related trends, competitor tactics, deal performance and customer behaviors including but not limited to Utilization Management, Coverage Trends, Policy Impacts, YOY trends, Claims analysis, etc. Evaluate Pain Patient Support Program out of pocket cost support programs impact, quantifying Fill Rate impact of Commercial Claims coverage support , Medicaid Part D coverage , Limited voucher programs , External Savings program and other out-of-pocket savings impact and scenarios. In depth analysis of Retail stocking related metrics using IntegriChain EDI 852 and 867 data, as well as IQVIA dispense data, combining with Claims data to understand inventory and stock levels, forecast stocking metrics and visualize trends. Collaborate with cross-functional teams, including Digital Technology & Engineering (DTE) and Global Insights Analytics & Commercial Operations (GIACO), to interpret business trends and support data-driven storytelling. Partner with key market access teams (e.g., Market Access Strategy, Pricing, Analytics & Contract Management, Payer field teams) to integrate insights into strategic discussions. Responsible for pain data quality initiatives, regular reporting and dashboards, including monitoring reports and data feeds for anomalies, identifying, explaining and remediating any variances if necessary and conducting necessary maintenance and upgrade activities. Lead pain technology and infrastructure requests with DTE, inclusive of requirements gathering and translations, user acceptance testing. Collaborate closely with Payer Field teams to respond to data inquiries and supply necessary account level metrics Communicate key findings related to utilization management, tiering, formulary/medical policy changes, and their impact on market access dynamics.

Requirements

• Bachelor’s degree in a quantitative discipline (e.g., Engineering, Statistics, Economics, Finance) required; advanced degree (MBA, MS, PhD) preferred.
• 3+ years of experience in the biotech/pharmaceutical industry or biopharma consulting, with a focus on Managed Markets, Market Access, or healthcare analytics.
• 3+ years of experience developing analytics that inform value, access, reimbursement, or contracting strategies.
• Proficiency in data analytics and evolving U.S. Market Access strategies, including payer account management, channel dynamics, and reimbursement models.
• Experience working with syndicated Market Access databases (e.g., IQVIA Xponent, MMIT) and distribution/shipment data (e.g., 852, 867, Integrichain).
• Strong analytical skills with proficiency in Excel, SQL, and PowerBI.
• Familiarity in additional tools like Python and Snowflake is a plus.
• Ability to collaborate with internal and external stakeholders to generate insights and support decision-making.
• Analytical thinker with the ability to identify key trends and synthesize complex information into actionable insights.
• Strong written and verbal communication skills, with the ability to present insights effectively to cross-functional teams and mid-level leadership.
• Flexible, adaptable, and able to navigate ambiguity in a fast-paced environment.
• Ability to support financial forecasting, analytics, and commercial launch planning through data-driven insights.
• Strong storytelling skills with the ability to summarize key insights into concise, impactful messages.

Nice To Haves

• Master’s Degree, MBA, MPH or a Master’s in a quantitative discipline is preferred.
• Good understanding of state/federal policies, government programs impacting market access, and statutory government pricing methodologies.
• 6+ years of pharmaceutical manufacturer market access experience and subject matter expertise with Health Plans, PBMs, Hospital Systems, Specialty Pharmacies and Healthcare Policy stakeholders.
• Diverse US product launch experience across different therapeutic areas strongly preferred.

Responsibilities

• Support the development of insights to strengthen Vertex’s leadership in Pain Therapy Area and contribute to broader market access portfolio strategies by analyzing trends in the evolving market access landscape, to drive in-line brands and pipeline asset advancements in Pain therapy area.
• Execute analytical insights to inform US market access in-market growth activities within Pain, including evaluating in-market analogues for informing market access strategy, pricing & contracting, payer/PBM landscape, clinic/hospital economics, etc.
• Conduct Payer Access analytics to quantify and validate market access-related trends, competitor tactics, deal performance and customer behaviors including but not limited to Utilization Management, Coverage Trends, Policy Impacts, YOY trends, Claims analysis, etc.
• Evaluate Pain Patient Support Program out of pocket cost support programs impact, quantifying Fill Rate impact of Commercial Claims coverage support , Medicaid Part D coverage , Limited voucher programs , External Savings program and other out-of-pocket savings impact and scenarios.
• In depth analysis of Retail stocking related metrics using IntegriChain EDI 852 and 867 data, as well as IQVIA dispense data, combining with Claims data to understand inventory and stock levels, forecast stocking metrics and visualize trends.
• Collaborate with cross-functional teams, including Digital Technology & Engineering (DTE) and Global Insights Analytics & Commercial Operations (GIACO), to interpret business trends and support data-driven storytelling.
• Partner with key market access teams (e.g., Market Access Strategy, Pricing, Analytics & Contract Management, Payer field teams) to integrate insights into strategic discussions.
• Responsible for pain data quality initiatives, regular reporting and dashboards, including monitoring reports and data feeds for anomalies, identifying, explaining and remediating any variances if necessary and conducting necessary maintenance and upgrade activities.
• Lead pain technology and infrastructure requests with DTE, inclusive of requirements gathering and translations, user acceptance testing.
• Collaborate closely with Payer Field teams to respond to data inquiries and supply necessary account level metrics
• Communicate key findings related to utilization management, tiering, formulary/medical policy changes, and their impact on market access dynamics.

Benefits

• medical
• dental
• vision benefits
• generous paid time off (including a week-long company shutdown in the Summer and the Winter)
• educational assistance programs including student loan repayment
• a generous commuting subsidy
• matching charitable donations
• 401(k)

What This Job Offers

• Job Type: Full-time
• Career Level: Mid Level
• Number of Employees: 5,001-10,000 employees