Co-Op, Process Development

BlueRock Therapeutics • New York City, NY

9h • $30 - $30 • Onsite

About The Position

BlueRock Therapeutics LP is a clinical stage cell therapy harnessing the power of cell therapy to create a pipeline of new medicines for people suffering from neurological and ophthalmic diseases. Two of our novel investigational cell therapies, bemdaneprocel (BRT-DA01) for the treatment of Parkinson’s disease and OpCT-001 for the treatment of primary photoreceptor diseases are clinical stage programs. BlueRock was founded in 2016 as a joint venture of Versant Ventures and Leaps by Bayer. Our culture is defined by the courage to persist regardless of the challenge, the urgency to transform medicine and deliver hope, integrity guided by mission, and community-mindedness with the understanding that we are all part of something bigger than ourselves. Our foundational science harnesses the ability to create and then direct the differentiation of universal pluripotent stem cells into authentic, functional cells that can be used as allogeneic cellular therapies to treat a broad array of diseases. We can also further engineer these cells, enabling them to produce enzymes, antibodies, and other proteins for additional therapeutic benefit. We are passionate about delivering on the promise of cellular and gene therapy, shaping the future of cellular medicine, and delivering new therapies to millions of patients with treatment options. We are seeking individuals who are collaborative, thrive in a fun and dynamic culture, and are steadfast in the commitment to advance cutting-edge cellular therapies to impact patients’ lives. The Process Development Co-Op is responsible for providing support for our technological and innovative advancement of PSC biology, characterization, and differentiation. The ideal candidate will be excited and motivated to join a team tackling new challenges and innovations in the cell therapy space. The individual will be involved in hands-on work, and participate in executing experiments, documenting experiment details, and analyzing datasets. This project will cover an end-to-end process for culturing and differentiating PSCs, which includes cell culture techniques, bioreactor process development, cryopreservation, and analytical assessments.

Requirements

• Recently graduated or currently enrolled in a degree program at an accredited college or university (Science or Engineering or related field of study).
• Possess the ability to work at least a 6-month assignment, full time on-site. Preferably a 12-month assignment.
• Must be 18 years of age by the start of the internship/co-op.
• Must have transportation to the site in Manhattan, NY, USA.
• This position is intended to be on-site full time and candidates will be informed should anything change.
• Excellent organizational and documentation skills, sufficient to multi-task in an extremely fast-paced environment with changing priorities.
• Positive, team-oriented, and problem-solving mindset.

Nice To Haves

• Experience in aseptic techniques, specifically with mammalian cell culture.
• Experience with cell counting, metabolite analysis, light microscopy, and immunoassays.
• Experience with bioreactor or fermentation systems.
• Programming experience.
• Excellent communication skills and ability to influence across multiple functions.

Responsibilities

• Assist in the development of PSC expansion methods, including 3D platform evaluation and cell characterization using different analytical methods.
• Follow standard operating procedures and document experimental data in a timely and accurate manner.
• Maintain and culture human pluripotent stem cells (PSCs) using aseptic technique in a BSL-2 laboratory, that will be used for downstream differentiation.
• Perform laboratory techniques like cell counting, imaging, and cell characterization assays.
• Critically assess experimental parameters and outcomes to maintain key quality attributes and troubleshoot issues.
• Analyze and present scientific data to colleagues at internal meetings.
• Perform additional duties to support the safe and efficient operation of the laboratory.
• Collaborate across teams and functions.
• Occasional supervised weekend work.

What This Job Offers

• Job Type: Full-time
• Career Level: Intern
• Education Level: No Education Listed